Humans excel at performing complex tasks by leveraging long-term memory across temporal and spatial experiences. In contrast, current Large Language Models (LLMs) struggle to effectively plan and act in dynamic, multi-room 3D environments. We posit that part of this limitation is due to the lack of proper 3D spatial-temporal memory modeling in LLMs. To address this, we first introduce 3DMem-Bench, a comprehensive benchmark comprising over 26,000 trajectories and 2,892 embodied tasks, question-answering and captioning, designed to evaluate an agent's ability to reason over long-term memory in 3D environments. Second, we propose 3DLLM-Mem, a novel dynamic memory management and fusion model for embodied spatial-temporal reasoning and actions in LLMs. Our model uses working memory tokens, which represents current observations, as queries to selectively attend to and fuse the most useful spatial and temporal features from episodic memory, which stores past observations and interactions. Our approach allows the agent to focus on task-relevant information while maintaining memory efficiency in complex, long-horizon environments. Experimental results demonstrate that 3DLLM-Mem achieves state-of-the-art performance across various tasks, outperforming the strongest baselines by 16.5% in success rate on 3DMem-Bench's most challenging in-the-wild embodied tasks.
Large-language models (LLMs) and chatbot agents are known to provide wrong outputs at times, and it was recently found that this can never be fully prevented. Hence, uncertainty quantification plays a crucial role, aiming to quantify the level of ambiguity in either one overall number or two numbers for aleatoric and epistemic uncertainty. This position paper argues that this traditional dichotomy of uncertainties is too limited for the open and interactive setup that LLM agents operate in when communicating with a user, and that we need to research avenues that enrich uncertainties in this novel scenario. We review the literature and find that popular definitions of aleatoric and epistemic uncertainties directly contradict each other and lose their meaning in interactive LLM agent settings. Hence, we propose three novel research directions that focus on uncertainties in such human-computer interactions: Underspecification uncertainties, for when users do not provide all information or define the exact task at the first go, interactive learning, to ask follow-up questions and reduce the uncertainty about the current context, and output uncertainties, to utilize the rich language and speech space to express uncertainties as more than mere numbers. We expect that these new ways of dealing with and communicating uncertainties will lead to LLM agent interactions that are more transparent, trustworthy, and intuitive.
This paper presents a novel approach for unified retrieval-augmented generation (RAG) systems using the recent emerging large language model (LLM) agent concept. Specifically, Agent LLM, which utilizes LLM as fundamental controllers, has become a promising approach to enable the interpretability of RAG tasks, especially for complex reasoning question-answering systems (e.g., multi-hop queries). Nonetheless, previous works mainly focus on solving RAG systems with either single-hop or multi-hop approaches separately, which limits the application of those approaches to real-world applications. In this study, we propose a trainable agent framework called Agent-UniRAG for unified retrieval-augmented LLM systems, which enhances the effectiveness and interpretability of RAG systems. The main idea is to design an LLM agent framework to solve RAG tasks step-by-step based on the complexity of the inputs, simultaneously including single-hop and multi-hop queries in an end-to-end manner. Furthermore, we introduce SynAgent-RAG, a synthetic dataset to enable the proposed agent framework for small open-source LLMs (e.g., Llama-3-8B). The results show comparable performances with closed-source and larger open-source LLMs across various RAG benchmarks. Our source code and dataset are publicly available for further exploitation.
Tactile perception is essential for embodied agents to understand physical attributes of objects that cannot be determined through visual inspection alone. While existing approaches have made progress in visual and language modalities for physical understanding, they fail to effectively incorporate tactile information that provides crucial haptic feedback for real-world interaction. In this paper, we present VTV-LLM, the first multi-modal large language model for universal Visuo-Tactile Video (VTV) understanding that bridges the gap between tactile perception and natural language. To address the challenges of cross-sensor and cross-modal integration, we contribute VTV150K, a comprehensive dataset comprising 150,000 video frames from 100 diverse objects captured across three different tactile sensors (GelSight Mini, DIGIT, and Tac3D), annotated with four fundamental tactile attributes (hardness, protrusion, elasticity, and friction). We develop a novel three-stage training paradigm that includes VTV enhancement for robust visuo-tactile representation, VTV-text alignment for cross-modal correspondence, and text prompt finetuning for natural language generation. Our framework enables sophisticated tactile reasoning capabilities including feature assessment, comparative analysis, scenario-based decision making and so on. Experimental evaluations demonstrate that VTV-LLM achieves superior performance in tactile video understanding tasks, establishing a foundation for more intuitive human-machine interaction in tactile domains.
While embodied agents have made significant progress in performing complex physical tasks, real-world applications demand more than pure task execution. The agents must collaborate with unfamiliar agents and human users, whose goals are often vague and implicit. In such settings, interpreting ambiguous instructions and uncovering underlying desires is essential for effective assistance. Therefore, fast and accurate desire alignment becomes a critical capability for embodied agents. In this work, we first develop a home assistance simulation environment HA-Desire that integrates an LLM-driven human user agent exhibiting realistic value-driven goal selection and communication. The ego agent must interact with this proxy user to infer and adapt to the user's latent desires. To achieve this, we present a novel framework FAMER for fast desire alignment, which introduces a desire-based mental reasoning mechanism to identify user intent and filter desire-irrelevant actions. We further design a reflection-based communication module that reduces redundant inquiries, and incorporate goal-relevant information extraction with memory persistence to improve information reuse and reduce unnecessary exploration. Extensive experiments demonstrate that our framework significantly enhances both task execution and communication efficiency, enabling embodied agents to quickly adapt to user-specific desires in complex embodied environments.
The rapid advancement of large language models (LLMs) has transformed the landscape of agentic information seeking capabilities through the integration of tools such as search engines and web browsers. However, current mainstream approaches for enabling LLM web search proficiency face significant challenges: supervised fine-tuning struggles with data production in open-search domains, while RL converges quickly, limiting their data utilization efficiency. To address these issues, we propose EvolveSearch, a novel iterative self-evolution framework that combines SFT and RL to enhance agentic web search capabilities without any external human-annotated reasoning data. Extensive experiments on seven multi-hop question-answering (MHQA) benchmarks demonstrate that EvolveSearch consistently improves performance across iterations, ultimately achieving an average improvement of 4.7\% over the current state-of-the-art across seven benchmarks, opening the door to self-evolution agentic capabilities in open web search domains.
Large Language Model-based Multi-Agent Systems (MASs) have emerged as a powerful paradigm for tackling complex tasks through collaborative intelligence. Nevertheless, the question of how agents should be structurally organized for optimal cooperation remains largely unexplored. In this position paper, we aim to gently redirect the focus of the MAS research community toward this critical dimension: develop topology-aware MASs for specific tasks. Specifically, the system consists of three core components - agents, communication links, and communication patterns - that collectively shape its coordination performance and efficiency. To this end, we introduce a systematic, three-stage framework: agent selection, structure profiling, and topology synthesis. Each stage would trigger new research opportunities in areas such as language models, reinforcement learning, graph learning, and generative modeling; together, they could unleash the full potential of MASs in complicated real-world applications. Then, we discuss the potential challenges and opportunities in the evaluation of multiple systems. We hope our perspective and framework can offer critical new insights in the era of agentic AI.
The rapid evolution of Large Language Model (LLM) agents has highlighted critical challenges in cross-vendor service discovery, interoperability, and communication. Existing protocols like model context protocol and agent-to-agent protocol have made significant strides in standardizing interoperability between agents and tools, as well as communication among multi-agents. However, there remains a lack of standardized protocols and solutions for service discovery across different agent and tool vendors. In this paper, we propose AgentDNS, a root domain naming and service discovery system designed to enable LLM agents to autonomously discover, resolve, and securely invoke third-party agent and tool services across organizational and technological boundaries. Inspired by the principles of the traditional DNS, AgentDNS introduces a structured mechanism for service registration, semantic service discovery, secure invocation, and unified billing. We detail the architecture, core functionalities, and use cases of AgentDNS, demonstrating its potential to streamline multi-agent collaboration in real-world scenarios. The source code will be published on https://github.com/agentdns.
With the advent of 6G communications, intelligent communication systems face multiple challenges, including constrained perception and response capabilities, limited scalability, and low adaptability in dynamic environments. This tutorial provides a systematic introduction to the principles, design, and applications of Large Artificial Intelligence Models (LAMs) and Agentic AI technologies in intelligent communication systems, aiming to offer researchers a comprehensive overview of cutting-edge technologies and practical guidance. First, we outline the background of 6G communications, review the technological evolution from LAMs to Agentic AI, and clarify the tutorial's motivation and main contributions. Subsequently, we present a comprehensive review of the key components required for constructing LAMs. We further categorize LAMs and analyze their applicability, covering Large Language Models (LLMs), Large Vision Models (LVMs), Large Multimodal Models (LMMs), Large Reasoning Models (LRMs), and lightweight LAMs. Next, we propose a LAM-centric design paradigm tailored for communications, encompassing dataset construction and both internal and external learning approaches. Building upon this, we develop an LAM-based Agentic AI system for intelligent communications, clarifying its core components such as planners, knowledge bases, tools, and memory modules, as well as its interaction mechanisms. We also introduce a multi-agent framework with data retrieval, collaborative planning, and reflective evaluation for 6G. Subsequently, we provide a detailed overview of the applications of LAMs and Agentic AI in communication scenarios. Finally, we summarize the research challenges and future directions in current studies, aiming to support the development of efficient, secure, and sustainable next-generation intelligent communication systems.
In this study, we propose a solution based on a multi-agent LLM architecture and a voice user interface (VUI) designed to update the knowledge base of a digital assistant. Its usability is evaluated in comparison to a more traditional graphical content management system (CMS), with a focus on understanding the relationship between user preferences and the complexity of the information being provided. The findings demonstrate that, while the overall usability of the VUI is rated lower than the graphical interface, it is already preferred by users for less complex tasks. Furthermore, the quality of content entered through the VUI is comparable to that achieved with the graphical interface, even for highly complex tasks. Obtained qualitative results suggest that a hybrid interface combining the strengths of both approaches could address the key challenges identified during the experiment, such as reducing cognitive load through graphical feedback while maintaining the intuitive nature of voice-based interactions. This work highlights the potential of conversational interfaces as a viable and effective method for knowledge management in specific business contexts.
Multi-agent systems based on large language models (LLMs) advance automatic task completion in various fields, where debate is a common cooperation form for agents to solve complicated problems with reasoning and cross-review to solidify answers. Assessing the individual contributions of agents within these debates is crucial for system refinement and outcome reliability. Traditional leave-one-out (LOO) method offers a clear framework for evaluating each agent's role but face challenges in LLM-based systems due to high computational costs and associated financial implications. This paper presents introspective-leave-one-out (IntrospecLOO), a simple yet effective prompting for approximation of LOO in LLM-powered multi-agent debates. IntrospecLOO introduces an additional querying round after standard debates, prompting agents to update their answers while ignoring responses from a designated agent. This strategy effectively isolates and gauges each participant's influence at a reduced query complexity compared to the original LOO approaches. Validation through experiments on three benchmark datasets confirms the effectiveness of IntrospecLOO.
The alignment between humans and machines is a critical challenge in artificial intelligence today. Reinforcement learning, which aims to maximize a reward function, is particularly vulnerable to the risks associated with poorly designed reward functions. Recent advancements has shown that Large Language Models (LLMs) for reward generation can outperform human performance in this context. We introduce VIRAL, a pipeline for generating and refining reward functions through the use of multi-modal LLMs. VIRAL autonomously creates and interactively improves reward functions based on a given environment and a goal prompt or annotated image. The refinement process can incorporate human feedback or be guided by a description generated by a video LLM, which explains the agent's policy in video form. We evaluated VIRAL in five Gymnasium environments, demonstrating that it accelerates the learning of new behaviors while ensuring improved alignment with user intent. The source-code and demo video are available at: https://github.com/VIRAL-UCBL1/VIRAL and https://youtu.be/t4_BXugBm9Q.
Recognizing vulnerabilities in stripped binary files presents a significant challenge in software security. Although some progress has been made in generating human-readable information from decompiled binary files with Large Language Models (LLMs), effectively and scalably detecting vulnerabilities within these binary files is still an open problem. This paper explores the novel application of LLMs to detect vulnerabilities within these binary files. We demonstrate the feasibility of identifying vulnerable programs through a combined approach of decompilation optimization to make the vulnerabilities more prominent and long-term memory for a larger context window, achieving state-of-the-art performance in binary vulnerability analysis. Our findings highlight the potential for LLMs to overcome the limitations of traditional analysis methods and advance the field of binary vulnerability detection, paving the way for more secure software systems. In this paper, we present Vul-BinLLM , an LLM-based framework for binary vulnerability detection that mirrors traditional binary analysis workflows with fine-grained optimizations in decompilation and vulnerability reasoning with an extended context. In the decompilation phase, Vul-BinLLM adds vulnerability and weakness comments without altering the code structure or functionality, providing more contextual information for vulnerability reasoning later. Then for vulnerability reasoning, Vul-BinLLM combines in-context learning and chain-of-thought prompting along with a memory management agent to enhance accuracy. Our evaluations encompass the commonly used synthetic dataset Juliet to evaluate the potential feasibility for analysis and vulnerability detection in C/C++ binaries. Our evaluations show that Vul-BinLLM is highly effective in detecting vulnerabilities on the compiled Juliet dataset.
With large language models (LLMs) demonstrating remarkable capabilities, there has been a surge in research on leveraging LLMs to build general-purpose multi-modal agents. However, existing approaches either rely on computationally expensive end-to-end training using large-scale multi-modal data or adopt tool-use methods that lack the ability to continuously learn and adapt to new environments. In this paper, we introduce EHC, a general agent capable of learning without parameter updates. EHC consists of a Hierarchical Memory Retrieval (HMR) module and a Task-Category Oriented Experience Learning (TOEL) module. The HMR module facilitates rapid retrieval of relevant memories and continuously stores new information without being constrained by memory capacity. The TOEL module enhances the agent's comprehension of various task characteristics by classifying experiences and extracting patterns across different categories. Extensive experiments conducted on multiple standard datasets demonstrate that EHC outperforms existing methods, achieving state-of-the-art performance and underscoring its effectiveness as a general agent for handling complex multi-modal tasks.
We introduce MapStory, an LLM-powered animation authoring tool that generates editable map animation sequences directly from natural language text. Given a user-written script, MapStory leverages an agentic architecture to automatically produce a scene breakdown, which decomposes the script into key animation building blocks such as camera movements, visual highlights, and animated elements. Our system includes a researcher component that accurately queries geospatial information by leveraging an LLM with web search, enabling the automatic extraction of relevant regions, paths, and coordinates while allowing users to edit and query for changes or additional information to refine the results. Additionally, users can fine-tune parameters of these blocks through an interactive timeline editor. We detail the system's design and architecture, informed by formative interviews with professional animators and an analysis of 200 existing map animation videos. Our evaluation, which includes expert interviews (N=5) and a usability study (N=12), demonstrates that MapStory enables users to create map animations with ease, facilitates faster iteration, encourages creative exploration, and lowers barriers to creating map-centric stories.
Large Language Models (LLMs) have demonstrated exceptional performance across a wide range of tasks. To further tailor LLMs to specific domains or applications, post-training techniques such as Supervised Fine-Tuning (SFT), Preference Learning, and model merging are commonly employed. While each of these methods has been extensively studied in isolation, the automated construction of complete post-training pipelines remains an underexplored area. Existing approaches typically rely on manual design or focus narrowly on optimizing individual components, such as data ordering or merging strategies. In this work, we introduce LaMDAgent (short for Language Model Developing Agent), a novel framework that autonomously constructs and optimizes full post-training pipelines through the use of LLM-based agents. LaMDAgent systematically explores diverse model generation techniques, datasets, and hyperparameter configurations, leveraging task-based feedback to discover high-performing pipelines with minimal human intervention. Our experiments show that LaMDAgent improves tool-use accuracy by 9.0 points while preserving instruction-following capabilities. Moreover, it uncovers effective post-training strategies that are often overlooked by conventional human-driven exploration. We further analyze the impact of data and model size scaling to reduce computational costs on the exploration, finding that model size scalings introduces new challenges, whereas scaling data size enables cost-effective pipeline discovery.
The increasing adoption of large language models (LLMs) with extended context windows necessitates efficient Key-Value Cache (KVC) management to optimize inference performance. Inference workloads like Retrieval-Augmented Generation (RAG) and agents exhibit high cache reusability, making efficient caching critical to reducing redundancy and improving speed. We analyze real-world KVC access patterns using publicly available traces and evaluate commercial key-value stores like Redis and state-of-the-art RDMA-based systems (CHIME [1] and Sherman [2]) for KVC metadata management. Our work demonstrates the lack of tailored storage solution for KVC prefilling, underscores the need for an efficient distributed caching system with optimized metadata management for LLM workloads, and provides insights into designing improved KVC management systems for scalable, low-latency inference.
Recent advancements in Large Language Models (LLMs) and autonomous agents have demonstrated remarkable capabilities across various domains. However, standalone agents frequently encounter limitations when handling complex tasks that demand extensive interactions and substantial computational resources. Although Multi-Agent Systems (MAS) alleviate some of these limitations through collaborative mechanisms like task decomposition, iterative communication, and role specialization, they typically remain resource-unaware, incurring significant inefficiencies due to high token consumption and excessive execution time. To address these limitations, we propose a resource-aware multi-agent system -- Co-Saving (meaning that multiple agents collaboratively engage in resource-saving activities), which leverages experiential knowledge to enhance operational efficiency and solution quality. Our key innovation is the introduction of "shortcuts" -- instructional transitions learned from historically successful trajectories -- which allows to bypass redundant reasoning agents and expedite the collective problem-solving process. Experiments for software development tasks demonstrate significant advantages over existing methods. Specifically, compared to the state-of-the-art MAS ChatDev, our method achieves an average reduction of 50.85% in token usage, and improves the overall code quality by 10.06%.
This study presents an innovative approach to urban mobility simulation by integrating a Large Language Model (LLM) with Agent-Based Modeling (ABM). Unlike traditional rule-based ABM, the proposed framework leverages LLM to enhance agent diversity and realism by generating synthetic population profiles, allocating routine and occasional locations, and simulating personalized routes. Using real-world data, the simulation models individual behaviors and large-scale mobility patterns in Taipei City. Key insights, such as route heat maps and mode-specific indicators, provide urban planners with actionable information for policy-making. Future work focuses on establishing robust validation frameworks to ensure accuracy and reliability in urban planning applications.
Safety reasoning is a recent paradigm where LLMs reason over safety policies before generating responses, thereby mitigating limitations in existing safety measures such as over-refusal and jailbreak vulnerabilities. However, implementing this paradigm is challenging due to the resource-intensive process of creating high-quality policy-embedded chain-of-thought (CoT) datasets while ensuring reasoning remains accurate and free from hallucinations or policy conflicts. To tackle this, we propose AIDSAFE: Agentic Iterative Deliberation for Safety Reasoning, a novel data generation recipe that leverages multi-agent deliberation to iteratively expand reasoning on safety policies. A data refiner stage in AIDSAFE ensures high-quality outputs by eliminating repetitive, redundant, and deceptive thoughts. AIDSAFE-generated CoTs provide a strong foundation for supervised fine-tuning (SFT)-based safety training. Additionally, to address the need of preference data in alignment stages, such as DPO training, we introduce a supplemental recipe that uses belief augmentation to create distinct selected and rejected CoT samples. Our evaluations demonstrate that AIDSAFE-generated CoTs achieve superior policy adherence and reasoning quality. Consequently, we show that fine-tuning open-source LLMs on these CoTs can significantly improve safety generalization and jailbreak robustness while maintaining acceptable utility and over-refusal accuracy. AIDSAFE-generated CoT datasets can be found here: https://huggingface.co/datasets/AmazonScience/AIDSAFE
Large Language Models (LLMs) as clinical agents require careful behavioral adaptation. While adept at reactive tasks (e.g., diagnosis reasoning), LLMs often struggle with proactive engagement, like unprompted identification of critical missing information or risks. We introduce BehaviorBench, a comprehensive dataset to evaluate agent behaviors across a clinical assistance spectrum, ranging from reactive query responses to proactive interventions (e.g., clarifying ambiguities, flagging overlooked critical data). Our BehaviorBench experiments reveal LLMs' inconsistent proactivity. To address this, we propose BehaviorSFT, a novel training strategy using behavioral tokens to explicitly condition LLMs for dynamic behavioral selection along this spectrum. BehaviorSFT boosts performance, achieving up to 97.3% overall Macro F1 on BehaviorBench and improving proactive task scores (e.g., from 95.0% to 96.5% for Qwen2.5-7B-Ins). Crucially, blind clinician evaluations confirmed BehaviorSFT-trained agents exhibit more realistic clinical behavior, striking a superior balance between helpful proactivity (e.g., timely, relevant suggestions) and necessary restraint (e.g., avoiding over-intervention) versus standard fine-tuning or explicit instructed agents.
Nuclear waste management requires rigorous regulatory compliance assessment, demanding advanced decision-support systems capable of addressing complex legal, environmental, and safety considerations. This paper presents a multi-agent Retrieval-Augmented Generation (RAG) system that integrates large language models (LLMs) with document retrieval mechanisms to enhance decision accuracy through structured agent collaboration. Through a structured 10-round discussion model, agents collaborate to assess regulatory compliance and safety requirements while maintaining document-grounded responses. Implemented on consumer-grade hardware, the system leverages Llama 3.2 and mxbai-embed-large-v1 embeddings for efficient retrieval and semantic representation. A case study of a proposed temporary nuclear waste storage site near Winslow, Arizona, demonstrates the framework's effectiveness. Results show the Regulatory Agent achieves consistently higher relevance scores in maintaining alignment with legal frameworks, while the Safety Agent effectively manages complex risk assessments requiring multifaceted analysis. The system demonstrates progressive improvement in agreement rates between agents across discussion rounds while semantic drift decreases, indicating enhanced decision-making consistency and response coherence. The system ensures regulatory decisions remain factually grounded, dynamically adapting to evolving regulatory frameworks through real-time document retrieval. By balancing automated assessment with human oversight, this framework offers a scalable and transparent approach to regulatory governance. These findings underscore the potential of AI-driven, multi-agent systems in advancing evidence-based, accountable, and adaptive decision-making for high-stakes environmental management scenarios.
Large language models (LLMs) have demonstrated strong potential in clinical question answering, with recent multi-agent frameworks further improving diagnostic accuracy via collaborative reasoning. However, we identify a recurring issue of Silent Agreement, where agents prematurely converge on diagnoses without sufficient critical analysis, particularly in complex or ambiguous cases. We present a new concept called Catfish Agent, a role-specialized LLM designed to inject structured dissent and counter silent agreement. Inspired by the ``catfish effect'' in organizational psychology, the Catfish Agent is designed to challenge emerging consensus to stimulate deeper reasoning. We formulate two mechanisms to encourage effective and context-aware interventions: (i) a complexity-aware intervention that modulates agent engagement based on case difficulty, and (ii) a tone-calibrated intervention articulated to balance critique and collaboration. Evaluations on nine medical Q&A and three medical VQA benchmarks show that our approach consistently outperforms both single- and multi-agent LLMs frameworks, including leading commercial models such as GPT-4o and DeepSeek-R1.
Automating robust hypothesis generation in open environments is pivotal for AI cognition. We introduce a novel framework integrating a multi-agent system, powered by Large Language Models (LLMs), with Inductive Logic Programming (ILP). Our system's LLM agents autonomously define a structured symbolic vocabulary (predicates) and relational templates , i.e., \emph{language bias} directly from raw textual data. This automated symbolic grounding (the construction of the language bias), traditionally an expert-driven bottleneck for ILP, then guides the transformation of text into facts for an ILP solver, which inductively learns interpretable rules. This approach overcomes traditional ILP's reliance on predefined symbolic structures and the noise-sensitivity of pure LLM methods. Extensive experiments in diverse, challenging scenarios validate superior performance, paving a new path for automated, explainable, and verifiable hypothesis generation.
With the rapid advancement of post-training techniques for reasoning and information seeking, large language models (LLMs) can incorporate a large quantity of retrieved knowledge to solve complex tasks. However, the limited context window of LLMs obstructs scaling the amount of external knowledge input, prohibiting further improvement, especially for tasks requiring significant amount of external knowledge. Existing context window extension methods inevitably cause information loss. LLM-based multi-agent methods emerge as a new paradigm to handle massive input in a distributional manner, where we identify two core bottlenecks in existing knowledge synchronization and reasoning processes. In this work, we develop a multi-agent framework, $\textbf{ExtAgents}$, to overcome the bottlenecks and enable better scalability in inference-time knowledge integration without longer-context training. Benchmarked with our enhanced multi-hop question answering test, $\textbf{$\boldsymbol{\infty}$Bench+}$, and other public test sets including long survey generation, ExtAgents significantly enhances the performance over existing non-training methods with the same amount of external knowledge input, regardless of whether it falls $\textit{within or exceeds the context window}$. Moreover, the method maintains high efficiency due to high parallelism. Further study in the coordination of LLM agents on increasing external knowledge input could benefit real-world applications.
Focused Ultrasound Ablation Surgery (FUAS) has emerged as a promising non-invasive therapeutic modality, valued for its safety and precision. Nevertheless, its clinical implementation entails intricate tasks such as multimodal image interpretation, personalized dose planning, and real-time intraoperative decision-making processes that demand intelligent assistance to improve efficiency and reliability. We introduce FUAS-Agents, an autonomous agent system that leverages the multimodal understanding and tool-using capabilities of large language models (LLMs). By integrating patient profiles and MRI data, FUAS-Agents orchestrates a suite of specialized medical AI tools, including segmentation, treatment dose prediction, and clinical guideline retrieval, to generate personalized treatment plans comprising MRI image, dose parameters, and therapeutic strategies. We evaluate the system in a uterine fibroid treatment scenario. Human assessment by four senior FUAS experts indicates that 82.5%, 82.5%, 87.5%, and 97.5% of the generated plans were rated 4 or above (on a 5-point scale) in terms of completeness, accuracy, fluency, and clinical compliance, respectively. These results demonstrate the potential of LLM-driven agents in enhancing decision-making across complex clinical workflows, and exemplify a translational paradigm that combines general-purpose models with specialized expert systems to solve practical challenges in vertical healthcare domains.
Effective engagement by large language models (LLMs) requires adapting responses to users' sociodemographic characteristics, such as age, occupation, and education level. While many real-world applications leverage dialogue history for contextualization, existing evaluations of LLMs' behavioral adaptation often focus on single-turn prompts. In this paper, we propose a framework to evaluate LLM adaptation when attributes are introduced either (1) explicitly via user profiles in the prompt or (2) implicitly through multi-turn dialogue history. We assess the consistency of model behavior across these modalities. Using a multi-agent pipeline, we construct a synthetic dataset pairing dialogue histories with distinct user profiles and employ questions from the Value Survey Module (VSM 2013) (Hofstede and Hofstede, 2016) to probe value expression. Our findings indicate that most models adjust their expressed values in response to demographic changes, particularly in age and education level, but consistency varies. Models with stronger reasoning capabilities demonstrate greater alignment, indicating the importance of reasoning in robust sociodemographic adaptation.
Patent claims define the scope of protection for an invention. If there are ambiguities in a claim, it is rejected by the patent office. In the US, this is referred to as indefiniteness (35 U.S.C {\S} 112(b)) and is among the most frequent reasons for patent application rejection. The development of automatic methods for patent definiteness examination has the potential to make patent drafting and examination more efficient, but no annotated dataset has been published to date. We introduce PEDANTIC (Patent Definiteness Examination Corpus), a novel dataset of 14k US patent claims from patent applications relating to Natural Language Processing (NLP), annotated with reasons for indefiniteness. We construct PEDANTIC using a fully automatic pipeline that retrieves office action documents from the USPTO and uses Large Language Models (LLMs) to extract the reasons for indefiniteness. A human validation study confirms the pipeline's accuracy in generating high-quality annotations. To gain insight beyond binary classification metrics, we implement an LLM-as-Judge evaluation that compares the free-form reasoning of every model-cited reason with every examiner-cited reason. We show that LLM agents based on Qwen 2.5 32B and 72B struggle to outperform logistic regression baselines on definiteness prediction, even though they often correctly identify the underlying reasons. PEDANTIC provides a valuable resource for patent AI researchers, enabling the development of advanced examination models. We will publicly release the dataset and code.
Recent interest in Multi-Agent Systems of Large Language Models (MAS LLMs) has led to an increase in frameworks leveraging multiple LLMs to tackle complex tasks. However, much of this literature appropriates the terminology of MAS without engaging with its foundational principles. In this position paper, we highlight critical discrepancies between MAS theory and current MAS LLMs implementations, focusing on four key areas: the social aspect of agency, environment design, coordination and communication protocols, and measuring emergent behaviours. Our position is that many MAS LLMs lack multi-agent characteristics such as autonomy, social interaction, and structured environments, and often rely on oversimplified, LLM-centric architectures. The field may slow down and lose traction by revisiting problems the MAS literature has already addressed. Therefore, we systematically analyse this issue and outline associated research opportunities; we advocate for better integrating established MAS concepts and more precise terminology to avoid mischaracterisation and missed opportunities.
In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic modeling struggles when systems become too complex, making functional modeling a more attractive approach. Our approach introduces a diagnostic framework grounded in the functional modeling principles of the Dynamic Master Logic (DML) model. It incorporates two coordinated LLM components, including an LLM-based workflow for automated construction of DML logic from system documentation and an LLM agent that facilitates interactive diagnostics. The generated logic is encoded into a structured KG, referred to as KG-DML, which supports hierarchical fault reasoning. Expert knowledge or operational data can also be incorporated to refine the model's precision and diagnostic depth. In the interaction phase, users submit natural language queries, which are interpreted by the LLM agent. The agent selects appropriate tools for structured reasoning, including upward and downward propagation across the KG-DML. Rather than embedding KG content into every prompt, the LLM agent distinguishes between diagnostic and interpretive tasks. For diagnostics, the agent selects and executes external tools that perform structured KG reasoning. For general queries, a Graph-based Retrieval-Augmented Generation (Graph-RAG) approach is used, retrieving relevant KG segments and embedding them into the prompt to generate natural explanations. A case study on an auxiliary feedwater system demonstrated the framework's effectiveness, with over 90% accuracy in key elements and consistent tool and argument extraction, supporting its use in safety-critical diagnostics.