LLM-agent - 2025-08-21

MedReseacher-R1: Expert-Level Medical Deep Researcher via A Knowledge-Informed Trajectory Synthesis Framework

Authors:Ailing Yu, Lan Yao, Jingnan Liu, Zhe Chen, Jiajun Yin, Yuan Wang, Xinhao Liao, Zhiling Ye, Ji Li, Yun Yue, Hansong Xiao, Hualei Zhou, Chunxiao Guo, Peng Wei, Jinjie Gu
Date:2025-08-20 17:51:20

Recent developments in Large Language Model (LLM)-based agents have shown impressive capabilities spanning multiple domains, exemplified by deep research systems that demonstrate superior performance on complex information-seeking and synthesis tasks. While general-purpose deep research agents have shown impressive capabilities, they struggle significantly with medical domain challenges, as evidenced by leading proprietary systems achieving limited accuracy on complex medical benchmarks. The key limitations are: (1) the model lacks sufficient dense medical knowledge for clinical reasoning, and (2) the framework is constrained by the absence of specialized retrieval tools tailored for medical contexts.We present a medical deep research agent that addresses these challenges through two core innovations. First, we develop a novel data synthesis framework using medical knowledge graphs, extracting the longest chains from subgraphs around rare medical entities to generate complex multi-hop question-answer pairs. Second, we integrate a custom-built private medical retrieval engine alongside general-purpose tools, enabling accurate medical information synthesis. Our approach generates 2100+ diverse trajectories across 12 medical specialties, each averaging 4.2 tool interactions.Through a two-stage training paradigm combining supervised fine-tuning and online reinforcement learning with composite rewards, our MedResearcher-R1-32B model demonstrates exceptional performance, establishing new state-of-the-art results on medical benchmarks while maintaining competitive performance on general deep research tasks. Our work demonstrates that strategic domain-specific innovations in architecture, tool design, and training data construction can enable smaller open-source models to outperform much larger proprietary systems in specialized domains.

HERAKLES: Hierarchical Skill Compilation for Open-ended LLM Agents

Authors:Thomas Carta, Clément Romac, Loris Gaven, Pierre-Yves Oudeyer, Olivier Sigaud, Sylvain Lamprier
Date:2025-08-20 14:50:28

Open-ended AI agents need to be able to learn efficiently goals of increasing complexity, abstraction and heterogeneity over their lifetime. Beyond sampling efficiently their own goals, autotelic agents specifically need to be able to keep the growing complexity of goals under control, limiting the associated growth in sample and computational complexity. To adress this challenge, recent approaches have leveraged hierarchical reinforcement learning (HRL) and language, capitalizing on its compositional and combinatorial generalization capabilities to acquire temporally extended reusable behaviours. Existing approaches use expert defined spaces of subgoals over which they instantiate a hierarchy, and often assume pre-trained associated low-level policies. Such designs are inadequate in open-ended scenarios, where goal spaces naturally diversify across a broad spectrum of difficulties. We introduce HERAKLES, a framework that enables a two-level hierarchical autotelic agent to continuously compile mastered goals into the low-level policy, executed by a small, fast neural network, dynamically expanding the set of subgoals available to the high-level policy. We train a Large Language Model (LLM) to serve as the high-level controller, exploiting its strengths in goal decomposition and generalization to operate effectively over this evolving subgoal space. We evaluate HERAKLES in the open-ended Crafter environment and show that it scales effectively with goal complexity, improves sample efficiency through skill compilation, and enables the agent to adapt robustly to novel challenges over time.

MCP-Universe: Benchmarking Large Language Models with Real-World Model Context Protocol Servers

Authors:Ziyang Luo, Zhiqi Shen, Wenzhuo Yang, Zirui Zhao, Prathyusha Jwalapuram, Amrita Saha, Doyen Sahoo, Silvio Savarese, Caiming Xiong, Junnan Li
Date:2025-08-20 13:28:58

The Model Context Protocol has emerged as a transformative standard for connecting large language models to external data sources and tools, rapidly gaining adoption across major AI providers and development platforms. However, existing benchmarks are overly simplistic and fail to capture real application challenges such as long-horizon reasoning and large, unfamiliar tool spaces. To address this critical gap, we introduce MCP-Universe, the first comprehensive benchmark specifically designed to evaluate LLMs in realistic and hard tasks through interaction with real-world MCP servers. Our benchmark encompasses 6 core domains spanning 11 different MCP servers: Location Navigation, Repository Management, Financial Analysis, 3D Design, Browser Automation, and Web Searching. To ensure rigorous evaluation, we implement execution-based evaluators, including format evaluators for agent format compliance, static evaluators for time-invariant content matching, and dynamic evaluators that automatically retrieve real-time ground truth for temporally sensitive tasks. Through extensive evaluation of leading LLMs, we find that even SOTA models such as GPT-5 (43.72%), Grok-4 (33.33%) and Claude-4.0-Sonnet (29.44%) exhibit significant performance limitations. In addition, our benchmark poses a significant long-context challenge for LLM agents, as the number of input tokens increases rapidly with the number of interaction steps. Moreover, it introduces an unknown-tools challenge, as LLM agents often lack familiarity with the precise usage of the MCP servers. Notably, enterprise-level agents like Cursor cannot achieve better performance than standard ReAct frameworks. Beyond evaluation, we open-source our extensible evaluation framework with UI support, enabling researchers and practitioners to seamlessly integrate new agents and MCP servers while fostering innovation in the rapidly evolving MCP ecosystem.

Entropy-Constrained Strategy Optimization in Urban Floods: A Multi-Agent Framework with LLM and Knowledge Graph Integration

Authors:Peilin Ji, Xiao Xue, Simeng Wang, Wenhao Yan
Date:2025-08-20 12:13:03

In recent years, the increasing frequency of extreme urban rainfall events has posed significant challenges to emergency scheduling systems. Urban flooding often leads to severe traffic congestion and service disruptions, threatening public safety and mobility. However, effective decision making remains hindered by three key challenges: (1) managing trade-offs among competing goals (e.g., traffic flow, task completion, and risk mitigation) requires dynamic, context-aware strategies; (2) rapidly evolving environmental conditions render static rules inadequate; and (3) LLM-generated strategies frequently suffer from semantic instability and execution inconsistency. Existing methods fail to align perception, global optimization, and multi-agent coordination within a unified framework. To tackle these challenges, we introduce H-J, a hierarchical multi-agent framework that integrates knowledge-guided prompting, entropy-constrained generation, and feedback-driven optimization. The framework establishes a closed-loop pipeline spanning from multi-source perception to strategic execution and continuous refinement. We evaluate H-J on real-world urban topology and rainfall data under three representative conditions: extreme rainfall, intermittent bursts, and daily light rain. Experiments show that H-J outperforms rule-based and reinforcement-learning baselines in traffic smoothness, task success rate, and system robustness. These findings highlight the promise of uncertainty-aware, knowledge-constrained LLM-based approaches for enhancing resilience in urban flood response.

Can LLM Agents Solve Collaborative Tasks? A Study on Urgency-Aware Planning and Coordination

Authors:João Vitor de Carvalho Silva, Douglas G. Macharet
Date:2025-08-20 11:44:10

The ability to coordinate actions across multiple agents is critical for solving complex, real-world problems. Large Language Models (LLMs) have shown strong capabilities in communication, planning, and reasoning, raising the question of whether they can also support effective collaboration in multi-agent settings. In this work, we investigate the use of LLM agents to solve a structured victim rescue task that requires division of labor, prioritization, and cooperative planning. Agents operate in a fully known graph-based environment and must allocate resources to victims with varying needs and urgency levels. We systematically evaluate their performance using a suite of coordination-sensitive metrics, including task success rate, redundant actions, room conflicts, and urgency-weighted efficiency. This study offers new insights into the strengths and failure modes of LLMs in physically grounded multi-agent collaboration tasks, contributing to future benchmarks and architectural improvements.

Who Sees What? Structured Thought-Action Sequences for Epistemic Reasoning in LLMs

Authors:Luca Annese, Sabrina Patania, Silvia Serino, Tom Foulsham, Silvia Rossi, Azzurra Ruggeri, Dimitri Ognibene
Date:2025-08-20 09:36:53

Recent advances in large language models (LLMs) and reasoning frameworks have opened new possibilities for improving the perspective -taking capabilities of autonomous agents. However, tasks that involve active perception, collaborative reasoning, and perspective taking (understanding what another agent can see or knows) pose persistent challenges for current LLM-based systems. This study investigates the potential of structured examples derived from transformed solution graphs generated by the Fast Downward planner to improve the performance of LLM-based agents within a ReAct framework. We propose a structured solution-processing pipeline that generates three distinct categories of examples: optimal goal paths (G-type), informative node paths (E-type), and step-by-step optimal decision sequences contrasting alternative actions (L-type). These solutions are further converted into ``thought-action'' examples by prompting an LLM to explicitly articulate the reasoning behind each decision. While L-type examples slightly reduce clarification requests and overall action steps, they do not yield consistent improvements. Agents are successful in tasks requiring basic attentional filtering but struggle in scenarios that required mentalising about occluded spaces or weighing the costs of epistemic actions. These findings suggest that structured examples alone are insufficient for robust perspective-taking, underscoring the need for explicit belief tracking, cost modelling, and richer environments to enable socially grounded collaboration in LLM-based agents.

Automated Optimization Modeling through Expert-Guided Large Language Model Reasoning

Authors:Beinuo Yang, Qishen Zhou, Junyi Li, Xingchen Su, Simon Hu
Date:2025-08-20 04:14:54

Optimization Modeling (OM) is essential for solving complex decision-making problems. However, the process remains time-consuming and error-prone, heavily relying on domain experts. While Large Language Models (LLMs) show promise in addressing these challenges through their natural language understanding and reasoning capabilities, current approaches face three critical limitations: high benchmark labeling error rates reaching up to 42\%, narrow evaluation scope that only considers optimal values, and computational inefficiency due to heavy reliance on multi-agent systems or model fine-tuning. In this work, we first enhance existing datasets through systematic error correction and more comprehensive annotation. Additionally, we introduce LogiOR, a new optimization modeling benchmark from the logistics domain, containing more complex problems with standardized annotations. Furthermore, we present ORThought, a novel framework that leverages expert-level optimization modeling principles through chain-of-thought reasoning to automate the OM process. Through extensive empirical evaluation, we demonstrate that ORThought outperforms existing approaches, including multi-agent frameworks, with particularly significant advantages on complex optimization problems. Finally, we provide a systematic analysis of our method, identifying critical success factors and failure modes, providing valuable insights for future research on LLM-based optimization modeling.

Organ-Agents: Virtual Human Physiology Simulator via LLMs

Authors:Rihao Chang, He Jiao, Weizhi Nie, Honglin Guo, Keliang Xie, Zhenhua Wu, Lina Zhao, Yunpeng Bai, Yongtao Ma, Lanjun Wang, Yuting Su, Xi Gao, Weijie Wang, Nicu Sebe, Bruno Lepri, Bingwei Sun
Date:2025-08-20 01:58:45

Recent advances in large language models (LLMs) have enabled new possibilities in simulating complex physiological systems. We introduce Organ-Agents, a multi-agent framework that simulates human physiology via LLM-driven agents. Each Simulator models a specific system (e.g., cardiovascular, renal, immune). Training consists of supervised fine-tuning on system-specific time-series data, followed by reinforcement-guided coordination using dynamic reference selection and error correction. We curated data from 7,134 sepsis patients and 7,895 controls, generating high-resolution trajectories across 9 systems and 125 variables. Organ-Agents achieved high simulation accuracy on 4,509 held-out patients, with per-system MSEs <0.16 and robustness across SOFA-based severity strata. External validation on 22,689 ICU patients from two hospitals showed moderate degradation under distribution shifts with stable simulation. Organ-Agents faithfully reproduces critical multi-system events (e.g., hypotension, hyperlactatemia, hypoxemia) with coherent timing and phase progression. Evaluation by 15 critical care physicians confirmed realism and physiological plausibility (mean Likert ratings 3.9 and 3.7). Organ-Agents also enables counterfactual simulations under alternative sepsis treatment strategies, generating trajectories and APACHE II scores aligned with matched real-world patients. In downstream early warning tasks, classifiers trained on synthetic data showed minimal AUROC drops (<0.04), indicating preserved decision-relevant patterns. These results position Organ-Agents as a credible, interpretable, and generalizable digital twin for precision diagnosis, treatment simulation, and hypothesis testing in critical care.

MultiFuzz: A Dense Retrieval-based Multi-Agent System for Network Protocol Fuzzing

Authors:Youssef Maklad, Fares Wael, Ali Hamdi, Wael Elsersy, Khaled Shaban
Date:2025-08-19 22:42:04

Traditional protocol fuzzing techniques, such as those employed by AFL-based systems, often lack effectiveness due to a limited semantic understanding of complex protocol grammars and rigid seed mutation strategies. Recent works, such as ChatAFL, have integrated Large Language Models (LLMs) to guide protocol fuzzing and address these limitations, pushing protocol fuzzers to wider exploration of the protocol state space. But ChatAFL still faces issues like unreliable output, LLM hallucinations, and assumptions of LLM knowledge about protocol specifications. This paper introduces MultiFuzz, a novel dense retrieval-based multi-agent system designed to overcome these limitations by integrating semantic-aware context retrieval, specialized agents, and structured tool-assisted reasoning. MultiFuzz utilizes agentic chunks of protocol documentation (RFC Documents) to build embeddings in a vector database for a retrieval-augmented generation (RAG) pipeline, enabling agents to generate more reliable and structured outputs, enhancing the fuzzer in mutating protocol messages with enhanced state coverage and adherence to syntactic constraints. The framework decomposes the fuzzing process into modular groups of agents that collaborate through chain-of-thought reasoning to dynamically adapt fuzzing strategies based on the retrieved contextual knowledge. Experimental evaluations on the Real-Time Streaming Protocol (RTSP) demonstrate that MultiFuzz significantly improves branch coverage and explores deeper protocol states and transitions over state-of-the-art (SOTA) fuzzers such as NSFuzz, AFLNet, and ChatAFL. By combining dense retrieval, agentic coordination, and language model reasoning, MultiFuzz establishes a new paradigm in autonomous protocol fuzzing, offering a scalable and extensible foundation for future research in intelligent agentic-based fuzzing systems.

Large Language Models are Highly Aligned with Human Ratings of Emotional Stimuli

Authors:Mattson Ogg, Chace Ashcraft, Ritwik Bose, Raphael Norman-Tenazas, Michael Wolmetz
Date:2025-08-19 19:22:00

Emotions exert an immense influence over human behavior and cognition in both commonplace and high-stress tasks. Discussions of whether or how to integrate large language models (LLMs) into everyday life (e.g., acting as proxies for, or interacting with, human agents), should be informed by an understanding of how these tools evaluate emotionally loaded stimuli or situations. A model's alignment with human behavior in these cases can inform the effectiveness of LLMs for certain roles or interactions. To help build this understanding, we elicited ratings from multiple popular LLMs for datasets of words and images that were previously rated for their emotional content by humans. We found that when performing the same rating tasks, GPT-4o responded very similarly to human participants across modalities, stimuli and most rating scales (r = 0.9 or higher in many cases). However, arousal ratings were less well aligned between human and LLM raters, while happiness ratings were most highly aligned. Overall LLMs aligned better within a five-category (happiness, anger, sadness, fear, disgust) emotion framework than within a two-dimensional (arousal and valence) organization. Finally, LLM ratings were substantially more homogenous than human ratings. Together these results begin to describe how LLM agents interpret emotional stimuli and highlight similarities and differences among biological and artificial intelligence in key behavioral domains.

Unintended Misalignment from Agentic Fine-Tuning: Risks and Mitigation

Authors:Dongyoon Hahm, Taywon Min, Woogyeol Jin, Kimin Lee
Date:2025-08-19 17:53:35

Beyond simple text generation, Large Language Models (LLMs) have evolved into agentic systems capable of planning and interacting with external tools to solve complex tasks. This evolution involves fine-tuning LLMs on agent-specific tasks to enhance their proficiency. However, safety concerns are frequently overlooked during this fine-tuning process. In this work, we show that aligned LLMs can become unintentionally misaligned, leading to a higher likelihood of executing harmful tasks and a reduced tendency to refuse them when fine-tuned to execute agentic tasks. To address these safety challenges, we propose Prefix INjection Guard (PING), a simple yet effective method that prepends automatically generated natural language prefixes to agent responses, guiding them to refuse harmful requests while preserving performance on benign tasks. Specifically, we introduce an iterative approach that alternates between (1) generating candidate prefixes and (2) selecting those that optimize both task performance and refusal behavior. Experimental results demonstrate that PING significantly enhances the safety of fine-tuned LLM agents without sacrificing their effectiveness. PING consistently outperforms existing prompting approaches across diverse benchmarks in both web navigation and code generation tasks. Our analysis of internal hidden states via linear probes reveals that prefix tokens are crucial for behavior modification, explaining the performance gains. WARNING: This paper contains contents that are unethical or offensive in nature.

Learning to Use AI for Learning: How Can We Effectively Teach and Measure Prompting Literacy for K-12 Students?

Authors:Ruiwei Xiao, Xinying Hou, Ying-Jui Tseng, Hsuan Nieu, Guanze Liao, John Stamper, Kenneth R. Koedinger
Date:2025-08-19 15:54:51

As Artificial Intelligence (AI) becomes increasingly integrated into daily life, there is a growing need to equip the next generation with the ability to apply, interact with, evaluate, and collaborate with AI systems responsibly. Prior research highlights the urgent demand from K-12 educators to teach students the ethical and effective use of AI for learning. To address this need, we designed an Large-Language Model (LLM)-based module to teach prompting literacy. This includes scenario-based deliberate practice activities with direct interaction with intelligent LLM agents, aiming to foster secondary school students' responsible engagement with AI chatbots. We conducted two iterations of classroom deployment in 11 authentic secondary education classrooms, and evaluated 1) AI-based auto-grader's capability; 2) students' prompting performance and confidence changes towards using AI for learning; and 3) the quality of learning and assessment materials. Results indicated that the AI-based auto-grader could grade student-written prompts with satisfactory quality. In addition, the instructional materials supported students in improving their prompting skills through practice and led to positive shifts in their perceptions of using AI for learning. Furthermore, data from Study 1 informed assessment revisions in Study 2. Analyses of item difficulty and discrimination in Study 2 showed that True/False and open-ended questions could measure prompting literacy more effectively than multiple-choice questions for our target learners. These promising outcomes highlight the potential for broader deployment and highlight the need for broader studies to assess learning effectiveness and assessment design.

LLM-Powered Virtual Patient Agents for Interactive Clinical Skills Training with Automated Feedback

Authors:Henrik Voigt, Yurina Sugamiya, Kai Lawonn, Sina Zarrieß, Atsuo Takanishi
Date:2025-08-19 15:31:37

Objective Structured Clinical Examinations (OSCEs) are essential for medical training, but they require significant resources, including professional actors and expert medical feedback. Although Large Language Models (LLMs) have introduced text-based virtual patients for communication practice, these simulations often lack the capability for richer, non-textual interactions. This paper presents a novel framework that significantly enhances LLM-based simulated patients by equipping them with action spaces, thereby enabling more realistic and dynamic patient behaviors that extend beyond text. Furthermore, our system incorporates virtual tutors that provide students with instant, personalized feedback on their performance at any time during these simulated encounters. We have conducted a rigorous evaluation of the framework's real-time performance, including system latency and component accuracy. Preliminary evaluations with medical experts assessed the naturalness and coherence of the simulated patients, as well as the usefulness and appropriateness of the virtual tutor's assessments. This innovative system provides medical students with a low-cost, accessible platform for personalized OSCE preparation at home.

The Collaboration Paradox: Why Generative AI Requires Both Strategic Intelligence and Operational Stability in Supply Chain Management

Authors:Soumyadeep Dhar
Date:2025-08-19 15:31:23

The rise of autonomous, AI-driven agents in economic settings raises critical questions about their emergent strategic behavior. This paper investigates these dynamics in the cooperative context of a multi-echelon supply chain, a system famously prone to instabilities like the bullwhip effect. We conduct computational experiments with generative AI agents, powered by Large Language Models (LLMs), within a controlled supply chain simulation designed to isolate their behavioral tendencies. Our central finding is the "collaboration paradox": a novel, catastrophic failure mode where theoretically superior collaborative AI agents, designed with Vendor-Managed Inventory (VMI) principles, perform even worse than non-AI baselines. We demonstrate that this paradox arises from an operational flaw where agents hoard inventory, starving the system. We then show that resilience is only achieved through a synthesis of two distinct layers: high-level, AI-driven proactive policy-setting to establish robust operational targets, and a low-level, collaborative execution protocol with proactive downstream replenishment to maintain stability. Our final framework, which implements this synthesis, can autonomously generate, evaluate, and quantify a portfolio of viable strategic choices. The work provides a crucial insight into the emergent behaviors of collaborative AI agents and offers a blueprint for designing stable, effective AI-driven systems for business analytics.

LLMind 2.0: Distributed IoT Automation with Natural Language M2M Communication and Lightweight LLM Agents

Authors:Yuyang Du, Qun Yang, Liujianfu Wang, Jingqi Lin, Hongwei Cui, Soung Chang Liew
Date:2025-08-19 15:17:31

Recent advances in large language models (LLMs) have sparked interest in their application to IoT and automation systems, particularly for facilitating device management through natural language instructions. However, existing centralized approaches face significant scalability challenges when managing and coordinating the collaboration between IoT devices of diverse capabilities in large-scale heterogeneous IoT systems. This paper introduces LLMind 2.0, a distributed IoT automation framework that addresses the scalability challenges through lightweight LLM-empowered device agents via natural language-based machine-to-machine (M2M) communication. Unlike previous LLM-controlled automation systems that rely on a centralized coordinator to generate device-specific code to be executed on individual devices, LLMind 2.0 distributes intelligence across individual devices through lightweight LLMs embedded in IoT devices. The central coordinator translates human instructions into simple subtasks described in natural human language, which are then processed by device-specific agents to generate device-specific code locally at the associated devices. This approach transcends device heterogeneity barriers by using natural language as a unified communication medium, enabling seamless collaboration between devices from different manufacturers. The system incorporates several key innovations: a Retrieval-Augmented Generation (RAG) mechanism for accurate subtask-to-API mapping, fine-tuned lightweight LLMs for reliable code generation, and a finite state machine-based task execution framework. Experimental validation in multi-robot warehouse scenarios and real-world WiFi network deployments demonstrates significant improvements in scalability, reliability, and privacy protection compared to the centralized approach.

Structured Agentic Workflows for Financial Time-Series Modeling with LLMs and Reflective Feedback

Authors:Yihao Ang, Yifan Bao, Lei Jiang, Jiajie Tao, Anthony K. H. Tung, Lukasz Szpruch, Hao Ni
Date:2025-08-19 15:14:49

Time-series data is central to decision-making in financial markets, yet building high-performing, interpretable, and auditable models remains a major challenge. While Automated Machine Learning (AutoML) frameworks streamline model development, they often lack adaptability and responsiveness to domain-specific needs and evolving objectives. Concurrently, Large Language Models (LLMs) have enabled agentic systems capable of reasoning, memory management, and dynamic code generation, offering a path toward more flexible workflow automation. In this paper, we introduce \textsf{TS-Agent}, a modular agentic framework designed to automate and enhance time-series modeling workflows for financial applications. The agent formalizes the pipeline as a structured, iterative decision process across three stages: model selection, code refinement, and fine-tuning, guided by contextual reasoning and experimental feedback. Central to our architecture is a planner agent equipped with structured knowledge banks, curated libraries of models and refinement strategies, which guide exploration, while improving interpretability and reducing error propagation. \textsf{TS-Agent} supports adaptive learning, robust debugging, and transparent auditing, key requirements for high-stakes environments such as financial services. Empirical evaluations on diverse financial forecasting and synthetic data generation tasks demonstrate that \textsf{TS-Agent} consistently outperforms state-of-the-art AutoML and agentic baselines, achieving superior accuracy, robustness, and decision traceability.

BetaWeb: Towards a Blockchain-enabled Trustworthy Agentic Web

Authors:Zihan Guo, Yuanjian Zhou, Chenyi Wang, Linlin You, Minjie Bian, Weinan Zhang
Date:2025-08-19 12:43:49

The rapid development of large language models (LLMs) has significantly propelled the development of artificial intelligence (AI) agents, which are increasingly evolving into diverse autonomous entities, advancing the LLM-based multi-agent systems (LaMAS). However, current agentic ecosystems remain fragmented and closed. Establishing an interconnected and scalable paradigm for Agentic AI has become a critical prerequisite. Although Agentic Web proposes an open architecture to break the ecosystem barriers, its implementation still faces core challenges such as privacy protection, data management, and value measurement. Existing centralized or semi-centralized paradigms suffer from inherent limitations, making them inadequate for supporting large-scale, heterogeneous, and cross-domain autonomous interactions. To address these challenges, this paper introduces the blockchain-enabled trustworthy Agentic Web (BetaWeb). By leveraging the inherent strengths of blockchain, BetaWeb not only offers a trustworthy and scalable infrastructure for LaMAS but also has the potential to advance the Web paradigm from Web3 (centered on data ownership) towards Web3.5, which emphasizes ownership of agent capabilities and the monetization of intelligence. Beyond a systematic examination of the BetaWeb framework, this paper presents a five-stage evolutionary roadmap, outlining the path of LaMAS from passive execution to advanced collaboration and autonomous governance. We also conduct a comparative analysis of existing products and discuss key challenges of BetaWeb from multiple perspectives. Ultimately, we argue that deep integration between blockchain and LaMAS can lay the foundation for a resilient, trustworthy, and sustainably incentivized digital ecosystem. A summary of the enabling technologies for each stage is available at https://github.com/MatZaharia/BetaWeb.

Agentic DraCor and the Art of Docstring Engineering: Evaluating MCP-empowered LLM Usage of the DraCor API

Authors:Peer Trilcke, Ingo Börner, Henny Sluyter-Gäthje, Daniil Skorinkin, Frank Fischer, Carsten Milling
Date:2025-08-19 12:21:21

This paper reports on the implementation and evaluation of a Model Context Protocol (MCP) server for DraCor, enabling Large Language Models (LLM) to autonomously interact with the DraCor API. We conducted experiments focusing on tool selection and application by the LLM, employing a qualitative approach that includes systematic observation of prompts to understand how LLMs behave when using MCP tools, evaluating "Tool Correctness", "Tool-Calling Efficiency", and "Tool-Use Reliability". Our findings highlight the importance of "Docstring Engineering", defined as reflexively crafting tool documentation to optimize LLM-tool interaction. Our experiments demonstrate both the promise of agentic AI for research in Computational Literary Studies and the essential infrastructure development needs for reliable Digital Humanities infrastructures.

Expertise-aware Multi-LLM Recruitment and Collaboration for Medical Decision-Making

Authors:Liuxin Bao, Zhihao Peng, Xiaofei Zhou, Runmin Cong, Jiyong Zhang, Yixuan Yuan
Date:2025-08-19 11:51:15

Medical Decision-Making (MDM) is a complex process requiring substantial domain-specific expertise to effectively synthesize heterogeneous and complicated clinical information. While recent advancements in Large Language Models (LLMs) show promise in supporting MDM, single-LLM approaches are limited by their parametric knowledge constraints and static training corpora, failing to robustly integrate the clinical information. To address this challenge, we propose the Expertise-aware Multi-LLM Recruitment and Collaboration (EMRC) framework to enhance the accuracy and reliability of MDM systems. It operates in two stages: (i) expertise-aware agent recruitment and (ii) confidence- and adversarial-driven multi-agent collaboration. Specifically, in the first stage, we use a publicly available corpus to construct an LLM expertise table for capturing expertise-specific strengths of multiple LLMs across medical department categories and query difficulty levels. This table enables the subsequent dynamic selection of the optimal LLMs to act as medical expert agents for each medical query during the inference phase. In the second stage, we employ selected agents to generate responses with self-assessed confidence scores, which are then integrated through the confidence fusion and adversarial validation to improve diagnostic reliability. We evaluate our EMRC framework on three public MDM datasets, where the results demonstrate that our EMRC outperforms state-of-the-art single- and multi-LLM methods, achieving superior diagnostic performance. For instance, on the MMLU-Pro-Health dataset, our EMRC achieves 74.45% accuracy, representing a 2.69% improvement over the best-performing closed-source model GPT- 4-0613, which demonstrates the effectiveness of our expertise-aware agent recruitment strategy and the agent complementarity in leveraging each LLM's specialized capabilities.

Self-Organizing Agent Network for LLM-based Workflow Automation

Authors:Yiming Xiong, Jian Wang, Bing Li, Yuhan Zhu, Yuqi Zhao
Date:2025-08-19 11:10:56

Recent multi-agent frameworks built upon large language models (LLMs) have demonstrated remarkable capabilities in complex task planning. However, in real-world enterprise environments, business workflows are typically composed through modularization and reuse of numerous subprocesses, resulting in intricate workflows characterized by lengthy and deeply nested execution paths. Such complexity poses significant challenges for LLM-driven orchestration, as extended reasoning chains and state-space explosions severely impact planning effectiveness and the proper sequencing of tool invocations. Therefore, developing an orchestration method with controllable structures capable of handling multi-layer nesting becomes a critical issue. To address this, we propose a novel structure-driven orchestration framework Self-Organizing Agent Network (SOAN). SOAN incrementally builds a formalized agent network by identifying and encapsulating structural units as independent agents, enhancing modularity and clarity in orchestration. Extensive evaluations were performed using multiple benchmarks as well as a real-world enterprise workflow dataset. Experimental results demonstrate that SOAN significantly outperforms state-of-the-art methods in terms of adaptability, fault tolerance, and execution efficiency.

CausalPlan: Empowering Efficient LLM Multi-Agent Collaboration Through Causality-Driven Planning

Authors:Minh Hoang Nguyen, Van Dai Do, Dung Nguyen, Thin Nguyen, Hung Le
Date:2025-08-19 10:37:20

Large language model (LLM) agents-especially smaller, open-source models-often produce causally invalid or incoherent actions in collaborative tasks due to their reliance on surface-level correlations rather than grounded causal reasoning. This limitation undermines their performance in terms of coordination and planning in dynamic environments. We address this challenge with CausalPlan, a two-phase framework that integrates explicit structural causal reasoning into the LLM planning process. At the core of CausalPlan is the Structural Causal Action (SCA) model, which learns a causal graph from agent trajectories to capture how prior actions and current environment states influence future decisions. This structure is then used to guide action selection by assigning causal scores to LLM-generated proposals, reweighting them accordingly, or falling back to causally grounded alternatives when needed. By embedding this causal knowledge directly into the decision loop, CausalPlan constrains planning to intervention-consistent behaviours without requiring fine-tuning of the LLM itself. We evaluate CausalPlan on the Overcooked-AI benchmark across five multi-agent coordination tasks and four LLMs of varying sizes: Gemma-7B, Llama-8B, Qwen-14B, and Llama-70B. Experimental results show that CausalPlan consistently reduces invalid actions and improves collaboration in both AI-AI and human-AI settings, outperforming strong reinforcement learning baselines. Our findings highlight the value of causality-driven planning for deploying efficient, interpretable, and generalisable multi-agent LLM systems.

Interpreting the Interpreter: Can We Model post-ECB Conferences Volatility with LLM Agents?

Authors:Umberto Collodel
Date:2025-08-19 08:48:05

This paper develops a novel method to simulate financial market reactions to European Central Bank (ECB) press conferences using a Large Language Model (LLM). We create a behavioral, agent-based simulation of 30 synthetic traders, each with distinct risk preferences, cognitive biases, and interpretive styles. These agents forecast Euro interest rate swap levels at 3-month, 2-year, and 10-year maturities, with the variation across forecasts serving as a measure of market uncertainty or disagreement. We evaluate three prompting strategies, naive, few-shot (enriched with historical data), and an advanced iterative 'LLM-as-a-Judge' framework, to assess the effect of prompt design on predictive performance. Even the naive approach generates a strong correlation (roughly 0.5) between synthetic disagreement and actual market outcomes, particularly for longer-term maturities. The LLM-as-a-Judge framework further improves accuracy at the first iteration. These results demonstrate that LLM-driven simulations can capture interpretive uncertainty beyond traditional measures, providing central banks with a practical tool to anticipate market reactions, refine communication strategies, and enhance financial stability.

AdaptJobRec: Enhancing Conversational Career Recommendation through an LLM-Powered Agentic System

Authors:Qixin Wang, Dawei Wang, Kun Chen, Yaowei Hu, Puneet Girdhar, Ruoteng Wang, Aadesh Gupta, Chaitanya Devella, Wenlai Guo, Shangwen Huang, Bachir Aoun, Greg Hayworth, Han Li, Xintao Wu
Date:2025-08-19 00:44:25

In recent years, recommendation systems have evolved from providing a single list of recommendations to offering a comprehensive suite of topic focused services. To better accomplish this task, conversational recommendation systems (CRS) have progressed from basic retrieval augmented LLM generation to agentic systems with advanced reasoning and self correction capabilities. However, agentic systems come with notable response latency, a longstanding challenge for conversational recommendation systems. To balance the trade off between handling complex queries and minimizing latency, we propose AdaptJobRec, the first conversational job recommendation system that leverages autonomous agent to integrate personalized recommendation algorithm tools. The system employs a user query complexity identification mechanism to minimize response latency. For straightforward queries, the agent directly selects the appropriate tool for rapid responses. For complex queries, the agent uses the memory processing module to filter chat history for relevant content, then passes the results to the intelligent task decomposition planner, and finally executes the tasks using personalized recommendation tools. Evaluation on Walmart's real world career recommendation scenarios demonstrates that AdaptJobRec reduces average response latency by up to 53.3% compared to competitive baselines, while significantly improving recommendation accuracy.

Large Language Models as Visualization Agents for Immersive Binary Reverse Engineering

Authors:Dennis Brown, Samuel Mulder
Date:2025-08-19 00:24:01

Immersive virtual reality (VR) offers affordances that may reduce cognitive complexity in binary reverse engineering (RE), enabling embodied and external cognition to augment the RE process through enhancing memory, hypothesis testing, and visual organization. In prior work, we applied a cognitive systems engineering approach to identify an initial set of affordances and implemented a VR environment to support RE through spatial persistence and interactivity. In this work, we extend that platform with an integrated large language model (LLM) agent capable of querying binary analysis tools, answering technical questions, and dynamically generating immersive 3D visualizations in alignment with analyst tasks. We describe the system architecture and our evaluation process and results. Our pilot study shows that while LLMs can generate meaningful 3D call graphs (for small programs) that align with design principles, output quality varies widely. This work raises open questions about the potential for LLMs to function as visualization agents, constructing 3D representations that reflect cognitive design principles without explicit training.

Datarus-R1: An Adaptive Multi-Step Reasoning LLM for Automated Data Analysis

Authors:Ayoub Ben Chaliah, Hela Dellagi
Date:2025-08-18 21:58:18

We present Datarus-R1-14B, a 14 B-parameter open-weights language model fine-tuned from Qwen 2.5-14B-Instruct to act as a virtual data analyst and graduate-level problem solver. Datarus is trained not on isolated question-answer pairs but on full analytical trajectories including reasoning steps, code execution, error traces, self-corrections, and final conclusions, all captured in a ReAct-style notebook format spanning finance, medicine, numerical analysis, and other quantitative domains. Our training pipeline combines (i) a trajectory-centric synthetic data generator that yielded 144 000 tagged notebook episodes, (ii) a dual-reward framework blending a lightweight tag-based structural signal with a Hierarchical Reward Model (HRM) that scores both single-step soundness and end-to-end coherence, and (iii) a memory-optimized implementation of Group Relative Policy Optimization (GRPO) featuring KV-cache reuse, sequential generation, and reference-model sharding. A cosine curriculum smoothly shifts emphasis from structural fidelity to semantic depth, reducing the format collapse and verbosity that often plague RL-aligned LLMs. A central design choice in Datarus is it dual reasoning interface. In agentic mode the model produces ReAct-tagged steps that invoke Python tools to execute real code; in reflection mode it outputs compact Chain-of-Thought (CoT) traces delimited by and tags. On demanding postgraduate-level problems, Datarus exhibits an "AHA-moment" pattern: it sketches hypotheses, revises them once or twice, and converges avoiding the circular, token-inflating loops common to contemporary systems. Across standard public benchmarks Datarus surpasses similar size models and even reaches the level of larger reasoning models such as QwQ-32B achieving up to 30% higher accuracy on AIME 2024/2025 and LiveCodeBench while emitting 18-49% fewer tokens per solution.

LOOP: A Plug-and-Play Neuro-Symbolic Framework for Enhancing Planning in Autonomous Systems

Authors:Ronit Virwani, Ruchika Suryawanshi
Date:2025-08-18 21:21:21

Planning is one of the most critical tasks in autonomous systems, where even a small error can lead to major failures or million-dollar losses. Current state-of-the-art neural planning approaches struggle with complex domains, producing plans with missing preconditions, inconsistent goals, and hallucinations. While classical planners provide logical guarantees, they lack the flexibility and natural language understanding capabilities needed for modern autonomous systems. Existing neuro-symbolic approaches use one-shot translation from natural language to formal plans, missing the opportunity for neural and symbolic components to work and refine solutions together. To address this gap, we develop LOOP -- a novel neuro-symbolic planning framework that treats planning as an iterative conversation between neural and symbolic components rather than simple translation. LOOP integrates 13 coordinated neural features including graph neural networks for spatial relationships, multi-agent validation for consensus-based correctness, hierarchical decomposition for complex task management, and causal memory that learns from both successes and failures. Unlike existing approaches, LOOP generates PDDL specifications, refines them iteratively based on symbolic feedback, and builds a causal knowledge base from execution traces. LOOP was evaluated on six standard IPC benchmark domains, where it achieved 85.8% success rate compared to LLM+P (55.0%), LLM-as-Planner (19.2%), and Tree-of-Thoughts (3.3%). This work shows that the key to reliable planning is not in choosing between neural networks or symbolic reasoners but it lies in making them actually ``talk'' to each other during the entire process. LOOP provides a thorough blueprint for building autonomous systems that can finally be trusted with critical real-world applications.

Exploring Autonomous Agents: A Closer Look at Why They Fail When Completing Tasks

Authors:Ruofan Lu, Yichen Li, Yintong Huo
Date:2025-08-18 17:55:22

Autonomous agent systems powered by Large Language Models (LLMs) have demonstrated promising capabilities in automating complex tasks. However, current evaluations largely rely on success rates without systematically analyzing the interactions, communication mechanisms, and failure causes within these systems. To bridge this gap, we present a benchmark of 34 representative programmable tasks designed to rigorously assess autonomous agents. Using this benchmark, we evaluate three popular open-source agent frameworks combined with two LLM backbones, observing a task completion rate of approximately 50%. Through in-depth failure analysis, we develop a three-tier taxonomy of failure causes aligned with task phases, highlighting planning errors, task execution issues, and incorrect response generation. Based on these insights, we propose actionable improvements to enhance agent planning and self-diagnosis capabilities. Our failure taxonomy, together with mitigation advice, provides an empirical foundation for developing more robust and effective autonomous agent systems in the future.

AutoBnB-RAG: Enhancing Multi-Agent Incident Response with Retrieval-Augmented Generation

Authors:Zefang Liu, Arman Anwar
Date:2025-08-18 17:22:51

Incident response (IR) requires fast, coordinated, and well-informed decision-making to contain and mitigate cyber threats. While large language models (LLMs) have shown promise as autonomous agents in simulated IR settings, their reasoning is often limited by a lack of access to external knowledge. In this work, we present AutoBnB-RAG, an extension of the AutoBnB framework that incorporates retrieval-augmented generation (RAG) into multi-agent incident response simulations. Built on the Backdoors & Breaches (B&B) tabletop game environment, AutoBnB-RAG enables agents to issue retrieval queries and incorporate external evidence during collaborative investigations. We introduce two retrieval settings: one grounded in curated technical documentation (RAG-Wiki), and another using narrative-style incident reports (RAG-News). We evaluate performance across eight team structures, including newly introduced argumentative configurations designed to promote critical reasoning. To validate practical utility, we also simulate real-world cyber incidents based on public breach reports, demonstrating AutoBnB-RAG's ability to reconstruct complex multi-stage attacks. Our results show that retrieval augmentation improves decision quality and success rates across diverse organizational models. This work demonstrates the value of integrating retrieval mechanisms into LLM-based multi-agent systems for cybersecurity decision-making.

WebMall -- A Multi-Shop Benchmark for Evaluating Web Agents

Authors:Ralph Peeters, Aaron Steiner, Luca Schwarz, Julian Yuya Caspary, Christian Bizer
Date:2025-08-18 15:41:22

LLM-based web agents have the potential to automate long-running web tasks, such as finding offers for specific products in multiple online shops and subsequently ordering the cheapest products that meet the users needs. This paper introduces WebMall, a multi-shop online shopping benchmark for evaluating the effectiveness and efficiency of web agents for comparison-shopping. WebMall consists of four simulated online shops populated with authentic product offers sourced from the Common Crawl, alongside a suite of 91 cross-shop tasks. These tasks include basic tasks such as finding specific products in multiple shops, performing price comparisons, adding items to the shopping cart, and completing checkout. Advanced tasks involve searching for products based on vague requirements, identifying suitable substitutes, and finding compatible products. Compared to existing e-commerce benchmarks, such as WebShop or ShoppingBench, WebMall introduces comparison-shopping tasks across multiple shops. Furthermore, the product offers are more heterogeneous, as they originate from hundreds of distinct real-world shops. The tasks in WebMall require longer interaction trajectories than those in WebShop, while remaining representative of real-world shopping behaviors. We evaluate eight baseline agents on WebMall, varying in observation modality, memory utilization, and underlying large language model (GPT 4.1 and Claude Sonnet 4). The best-performing configurations achieve completion rates of 75% and 53%, and F1 scores of 87% and 63%, on the basic and advanced task sets, respectively. WebMall is publicly released to facilitate research on web agents and to promote advancements in navigation, reasoning, and efficiency within e-commerce scenarios.

Analyzing Information Sharing and Coordination in Multi-Agent Planning

Authors:Tianyue Ou, Saujas Vaduguru, Daniel Fried
Date:2025-08-18 14:57:02

Multi-agent systems (MASs) have pushed the boundaries of large language model (LLM) agents in domains such as web research and software engineering. However, long-horizon, multi-constraint planning tasks involve conditioning on detailed information and satisfying complex interdependent constraints, which can pose a challenge for these systems. In this study, we construct an LLM-based MAS for a travel planning task which is representative of these challenges. We evaluate the impact of a notebook to facilitate information sharing, and evaluate an orchestrator agent to improve coordination in free form conversation between agents. We find that the notebook reduces errors due to hallucinated details by 18%, while an orchestrator directs the MAS to focus on and further reduce errors by up to 13.5% within focused sub-areas. Combining both mechanisms achieves a 25% final pass rate on the TravelPlanner benchmark, a 17.5% absolute improvement over the single-agent baseline's 7.5% pass rate. These results highlight the potential of structured information sharing and reflective orchestration as key components in MASs for long horizon planning with LLMs.