Large Language Models (LLMs), when paired with prompt-based tasks, have significantly reduced data annotation costs and reliance on human annotators. However, evaluating the quality of their annotations remains challenging in dynamic, unsupervised environments where oracle feedback is scarce and conventional methods fail. To address this challenge, we propose a novel agentic annotation paradigm, where a student model collaborates with a noisy teacher (the LLM) to assess and refine annotation quality without relying on oracle feedback. The student model, acting as an unsupervised feedback mechanism, employs a user preference-based majority voting strategy to evaluate the consistency of the LLM outputs. To systematically measure the reliability of LLM-generated annotations, we introduce the Consistent and Inconsistent (CAI) Ratio, a novel unsupervised evaluation metric. The CAI Ratio not only quantifies the annotation quality of the noisy teacher under limited user preferences but also plays a critical role in model selection, enabling the identification of robust LLMs in dynamic, unsupervised environments. Applied to ten open-domain NLP datasets across four LLMs, the CAI Ratio demonstrates a strong positive correlation with LLM accuracy, establishing it as an essential tool for unsupervised evaluation and model selection in real-world settings.
Developing autonomous LLM agents capable of making a series of intelligent decisions to solve complex, real-world tasks is a fast-evolving frontier. Like human cognitive development, agents are expected to acquire knowledge and skills through exploration and interaction with the environment. Despite advances, the community still lacks a unified, interactive reinforcement learning (RL) framework that can effectively train such agents from scratch -- without relying on supervised fine-tuning (SFT) -- across diverse and realistic environments. To bridge this gap, we introduce AgentGym-RL, a new framework to train LLM agents for multi-turn interactive decision-making through RL. The framework features a modular and decoupled architecture, ensuring high flexibility and extensibility. It encompasses a wide variety of real-world scenarios, and supports mainstream RL algorithms. Furthermore, we propose ScalingInter-RL, a training approach designed for exploration-exploitation balance and stable RL optimization. In early stages, it emphasizes exploitation by restricting the number of interactions, and gradually shifts towards exploration with larger horizons to encourage diverse problem-solving strategies. In this way, the agent develops more diverse behaviors and is less prone to collapse under long horizons. We perform extensive experiments to validate the stability and effectiveness of both the AgentGym-RL framework and the ScalingInter-RL approach. Our agents match or surpass commercial models on 27 tasks across diverse environments. We offer key insights and will open-source the complete AgentGym-RL framework -- including code and datasets -- to empower the research community in developing the next generation of intelligent agents.
The efficiency of Bayesian optimization (BO) in chemistry is often hindered by sparse experimental data and complex reaction mechanisms. To overcome these limitations, we introduce ChemBOMAS, a new framework named LLM-Enhanced Multi-Agent System for accelerating BO in chemistry. ChemBOMAS's optimization process is enhanced by LLMs and synergistically employs two strategies: knowledge-driven coarse-grained optimization and data-driven fine-grained optimization. First, in the knowledge-driven coarse-grained optimization stage, LLMs intelligently decompose the vast search space by reasoning over existing chemical knowledge to identify promising candidate regions. Subsequently, in the data-driven fine-grained optimization stage, LLMs enhance the BO process within these candidate regions by generating pseudo-data points, thereby improving data utilization efficiency and accelerating convergence. Benchmark evaluations** further confirm that ChemBOMAS significantly enhances optimization effectiveness and efficiency compared to various BO algorithms. Importantly, the practical utility of ChemBOMAS was validated through wet-lab experiments conducted under pharmaceutical industry protocols, targeting conditional optimization for a previously unreported and challenging chemical reaction. In the wet experiment, ChemBOMAS achieved an optimal objective value of 96%. This was substantially higher than the 15% achieved by domain experts. This real-world success, together with strong performance on benchmark evaluations, highlights ChemBOMAS as a powerful tool to accelerate chemical discovery.
Creating large-scale verifiable training datasets for issue-resolving tasks is a critical yet notoriously difficult challenge. Existing methods on automating the Gym environment setup process for real-world issues suffer from low success rates and high overhead. Meanwhile, synthesizing new tasks within existing Gym environments leaves the vast pool of authentic, human-reported problems untapped. To maximize the utilization of existing Gym environments and also the rich data of issue-resolving history on GitHub, we introduce SWE-Mirror, a pipeline that distills a real-world issue's semantic essence, mirrors it into another repository with a configured Gym environment, and re-animates it as a verifiable issue-resolving task. SWE-Mirror reuses existing Gym environments along with the vast pool of issue-resolving history hosted on GitHub to construct a large-scale dataset of mirrored authentic and verifiable tasks. Applying SWE-Mirror to 40 repositories across 4 languages, we have curated a dataset with 60,671 issue-resolving tasks and demonstrated the value of our dataset by training and evaluating coding agents at various scale. Post-training experiments show that models trained with the dataset exhibit improvements in issue-resolving capabilities. Furthermore, by extending the dataset size to over 12,000 high-quality trajectories, we established a new state-of-the-art (SOTA) among Qwen2.5-Coder-Instruct based LLMs on the OpenHands agent framework, which increases the resolve rate on SWE-Bench-Verified by +21.8% for the 7B model and +46.0% for the 32B model and validates the effectiveness of our approach.
As Large Language Model (LLM) agents become increasingly capable of automating complex, multi-step tasks, the need for robust, secure, and predictable architectural patterns is paramount. This paper provides a comprehensive guide to the ``Plan-then-Execute'' (P-t-E) pattern, an agentic design that separates strategic planning from tactical execution. We explore the foundational principles of P-t-E, detailing its core components - the Planner and the Executor - and its architectural advantages in predictability, cost-efficiency, and reasoning quality over reactive patterns like ReAct (Reason + Act). A central focus is placed on the security implications of this design, particularly its inherent resilience to indirect prompt injection attacks by establishing control-flow integrity. We argue that while P-t-E provides a strong foundation, a defense-in-depth strategy is necessary, and we detail essential complementary controls such as the Principle of Least Privilege, task-scoped tool access, and sandboxed code execution. To make these principles actionable, this guide provides detailed implementation blueprints and working code references for three leading agentic frameworks: LangChain (via LangGraph), CrewAI, and AutoGen. Each framework's approach to implementing the P-t-E pattern is analyzed, highlighting unique features like LangGraph's stateful graphs for re-planning, CrewAI's declarative tool scoping for security, and AutoGen's built-in Docker sandboxing. Finally, we discuss advanced patterns, including dynamic re-planning loops, parallel execution with Directed Acyclic Graphs (DAGs), and the critical role of Human-in-the-Loop (HITL) verification, to offer a complete strategic blueprint for architects, developers, and security engineers aiming to build production-grade, resilient, and trustworthy LLM agents.
Specialized machine learning models, regardless of architecture and training, are susceptible to failures in deployment. With their increasing use in high risk situations, the ability to audit these models by determining their operational design domain (ODD) is crucial in ensuring safety and compliance. However, given the high-dimensional input spaces, this process often requires significant human resources and domain expertise. To alleviate this, we introduce \coolname, an LLM-Agent centric framework for automated generation of semantically relevant test cases to search for failure modes in specialized black-box models. By leveraging LLM-Agents as tool orchestrators, we aim to fit a uncertainty-aware failure distribution model on a learned text-embedding manifold by projecting the high-dimension input space to low-dimension text-embedding latent space. The LLM-Agent is tasked with iteratively building the failure landscape by leveraging tools for generating test-cases to probe the model-under-test (MUT) and recording the response. The agent also guides the search using tools to probe uncertainty estimate on the low dimensional manifold. We demonstrate this process in a simple case using models trained with missing digits on the MNIST dataset and in the real world setting of vision-based intruder detection for aerial vehicles.
The substantial data volumes encountered in modern particle physics and other domains of fundamental physics research allow (and require) the use of increasingly complex data analysis tools and workflows. While the use of machine learning (ML) tools for data analysis has recently proliferated, these tools are typically special-purpose algorithms that rely, for example, on encoded physics knowledge to reach optimal performance. In this work, we investigate a new and orthogonal direction: Using recent progress in large language models (LLMs) to create a team of agents -- instances of LLMs with specific subtasks -- that jointly solve data analysis-based research problems in a way similar to how a human researcher might: by creating code to operate standard tools and libraries (including ML systems) and by building on results of previous iterations. If successful, such agent-based systems could be deployed to automate routine analysis components to counteract the increasing complexity of modern tool chains. To investigate the capabilities of current-generation commercial LLMs, we consider the task of anomaly detection via the publicly available and highly-studied LHC Olympics dataset. Several current models by OpenAI (GPT-4o, o4-mini, GPT-4.1, and GPT-5) are investigated and their stability tested. Overall, we observe the capacity of the agent-based system to solve this data analysis problem. The best agent-created solutions mirror the performance of human state-of-the-art results.
As humans delegate more tasks and decisions to artificial intelligence (AI), we risk losing control of our individual and collective futures. Relatively simple algorithmic systems already steer human decision-making, such as social media feed algorithms that lead people to unintentionally and absent-mindedly scroll through engagement-optimized content. In this paper, we develop the idea of human agency by integrating philosophical and scientific theories of agency with AI-assisted evaluation methods: using large language models (LLMs) to simulate and validate user queries and to evaluate AI responses. We develop HumanAgencyBench (HAB), a scalable and adaptive benchmark with six dimensions of human agency based on typical AI use cases. HAB measures the tendency of an AI assistant or agent to Ask Clarifying Questions, Avoid Value Manipulation, Correct Misinformation, Defer Important Decisions, Encourage Learning, and Maintain Social Boundaries. We find low-to-moderate agency support in contemporary LLM-based assistants and substantial variation across system developers and dimensions. For example, while Anthropic LLMs most support human agency overall, they are the least supportive LLMs in terms of Avoid Value Manipulation. Agency support does not appear to consistently result from increasing LLM capabilities or instruction-following behavior (e.g., RLHF), and we encourage a shift towards more robust safety and alignment targets.
Generating regulatorily compliant Suspicious Activity Report (SAR) remains a high-cost, low-scalability bottleneck in Anti-Money Laundering (AML) workflows. While large language models (LLMs) offer promising fluency, they suffer from factual hallucination, limited crime typology alignment, and poor explainability -- posing unacceptable risks in compliance-critical domains. This paper introduces Co-Investigator AI, an agentic framework optimized to produce Suspicious Activity Reports (SARs) significantly faster and with greater accuracy than traditional methods. Drawing inspiration from recent advances in autonomous agent architectures, such as the AI Co-Scientist, our approach integrates specialized agents for planning, crime type detection, external intelligence gathering, and compliance validation. The system features dynamic memory management, an AI-Privacy Guard layer for sensitive data handling, and a real-time validation agent employing the Agent-as-a-Judge paradigm to ensure continuous narrative quality assurance. Human investigators remain firmly in the loop, empowered to review and refine drafts in a collaborative workflow that blends AI efficiency with domain expertise. We demonstrate the versatility of Co-Investigator AI across a range of complex financial crime scenarios, highlighting its ability to streamline SAR drafting, align narratives with regulatory expectations, and enable compliance teams to focus on higher-order analytical work. This approach marks the beginning of a new era in compliance reporting -- bringing the transformative benefits of AI agents to the core of regulatory processes and paving the way for scalable, reliable, and transparent SAR generation.
Large Language Models (LLMs), with their strong understanding and reasoning capabilities, are increasingly being explored for tackling optimization problems, especially in synergy with evolutionary computation. Despite rapid progress, however, the field still lacks a unified synthesis and a systematic taxonomy. This survey addresses this gap by providing a comprehensive review of recent developments and organizing them within a structured framework. We classify existing research into two main stages: LLMs for optimization modeling and LLMs for optimization solving. The latter is further divided into three paradigms according to the role of LLMs in the optimization workflow: LLMs as stand-alone optimizers, low-level LLMs embedded within optimization algorithms, and high-level LLMs for algorithm selection and generation. For each category, we analyze representative methods, distill technical challenges, and examine their interplay with traditional approaches. We also review interdisciplinary applications spanning the natural sciences, engineering, and machine learning. By contrasting LLM-driven and conventional methods, we highlight key limitations and research gaps, and point toward future directions for developing self-evolving agentic ecosystems for optimization. An up-to-date collection of related literature is maintained at https://github.com/ishmael233/LLM4OPT.
This study presents an Exploratory Retrieval-Augmented Planning (ExRAP) framework, designed to tackle continual instruction following tasks of embodied agents in dynamic, non-stationary environments. The framework enhances Large Language Models' (LLMs) embodied reasoning capabilities by efficiently exploring the physical environment and establishing the environmental context memory, thereby effectively grounding the task planning process in time-varying environment contexts. In ExRAP, given multiple continual instruction following tasks, each instruction is decomposed into queries on the environmental context memory and task executions conditioned on the query results. To efficiently handle these multiple tasks that are performed continuously and simultaneously, we implement an exploration-integrated task planning scheme by incorporating the {information-based exploration} into the LLM-based planning process. Combined with memory-augmented query evaluation, this integrated scheme not only allows for a better balance between the validity of the environmental context memory and the load of environment exploration, but also improves overall task performance. Furthermore, we devise a {temporal consistency refinement} scheme for query evaluation to address the inherent decay of knowledge in the memory. Through experiments with VirtualHome, ALFRED, and CARLA, our approach demonstrates robustness against a variety of embodied instruction following scenarios involving different instruction scales and types, and non-stationarity degrees, and it consistently outperforms other state-of-the-art LLM-based task planning approaches in terms of both goal success rate and execution efficiency.
Large Language Models (LLMs) often produce monolithic text that is hard to edit in parts, which can slow down collaborative workflows. We present componentization, an approach that decomposes model outputs into modular, independently editable units while preserving context. We describe Modular and Adaptable Output Decomposition (MAOD), which segments responses into coherent components and maintains links among them, and we outline the Component-Based Response Architecture (CBRA) as one way to implement this idea. Our reference prototype, MAODchat, uses a microservices design with state-machine-based decomposition agents, vendor-agnostic model adapters, and real-time component manipulation with recomposition. In an exploratory study with four participants from academic, engineering, and product roles, we observed that component-level editing aligned with several common workflows and enabled iterative refinement and selective reuse. Participants also mentioned possible team workflows. Our contributions are: (1) a definition of componentization for transforming monolithic outputs into manipulable units, (2) CBRA and MAODchat as a prototype architecture, (3) preliminary observations from a small user study, (4) MAOD as an algorithmic sketch for semantic segmentation, and (5) example Agent-to-Agent protocols for automated decomposition. We view componentization as a promising direction for turning passive text consumption into more active, component-level collaboration.
Structured prompting with XML tags has emerged as an effective way to steer large language models (LLMs) toward parseable, schema-adherent outputs in real-world systems. We develop a logic-first treatment of XML prompting that unifies (i) grammar-constrained decoding, (ii) fixed-point semantics over lattices of hierarchical prompts, and (iii) convergent human-AI interaction loops. We formalize a complete lattice of XML trees under a refinement order and prove that monotone prompt-to-prompt operators admit least fixed points (Knaster-Tarski) that characterize steady-state protocols; under a task-aware contraction metric on trees, we further prove Banach-style convergence of iterative guidance. We instantiate these results with context-free grammars (CFGs) for XML schemas and show how constrained decoding guarantees well-formedness while preserving task performance. A set of multi-layer human-AI interaction recipes demonstrates practical deployment patterns, including multi-pass "plan $\to$ verify $\to$ revise" routines and agentic tool use. We provide mathematically complete proofs and tie our framework to recent advances in grammar-aligned decoding, chain-of-verification, and programmatic prompting.
Recent advances in Large Language Models (LLMs) have driven interest in automating cybersecurity penetration testing workflows, offering the promise of faster and more consistent vulnerability assessment for enterprise systems. Existing LLM agents for penetration testing primarily rely on self-guided reasoning, which can produce inaccurate or hallucinated procedural steps. As a result, the LLM agent may undertake unproductive actions, such as exploiting unused software libraries or generating cyclical responses that repeat prior tactics. In this work, we propose a guided reasoning pipeline for penetration testing LLM agents that incorporates a deterministic task tree built from the MITRE ATT&CK Matrix, a proven penetration testing kll chain, to constrain the LLM's reaoning process to explicitly defined tactics, techniques, and procedures. This anchors reasoning in proven penetration testing methodologies and filters out ineffective actions by guiding the agent towards more productive attack procedures. To evaluate our approach, we built an automated penetration testing LLM agent using three LLMs (Llama-3-8B, Gemini-1.5, and GPT-4) and applied it to navigate 10 HackTheBox cybersecurity exercises with 103 discrete subtasks representing real-world cyberattack scenarios. Our proposed reasoning pipeline guided the LLM agent through 71.8\%, 72.8\%, and 78.6\% of subtasks using Llama-3-8B, Gemini-1.5, and GPT-4, respectively. Comparatively, the state-of-the-art LLM penetration testing tool using self-guided reasoning completed only 13.5\%, 16.5\%, and 75.7\% of subtasks and required 86.2\%, 118.7\%, and 205.9\% more model queries. This suggests that incorporating a deterministic task tree into LLM reasoning pipelines can enhance the accuracy and efficiency of automated cybersecurity assessments
Effectively managing intellectual property is a significant challenge. Traditional methods for patent analysis depend on labor-intensive manual searches and rigid keyword matching. These approaches are often inefficient and struggle to reveal the complex relationships hidden within large patent datasets, hindering strategic decision-making. To overcome these limitations, we introduce KLIPA, a novel framework that leverages a knowledge graph and a large language model (LLM) to significantly advance patent analysis. Our approach integrates three key components: a structured knowledge graph to map explicit relationships between patents, a retrieval-augmented generation(RAG) system to uncover contextual connections, and an intelligent agent that dynamically determines the optimal strategy for resolving user queries. We validated KLIPA on a comprehensive, real-world patent database, where it demonstrated substantial improvements in knowledge extraction, discovery of novel connections, and overall operational efficiency. This combination of technologies enhances retrieval accuracy, reduces reliance on domain experts, and provides a scalable, automated solution for any organization managing intellectual property, including technology corporations and legal firms, allowing them to better navigate the complexities of strategic innovation and competitive intelligence.
Large Language Models (LLMs) have been increasingly integrated into computer-use agents, which can autonomously operate tools on a user's computer to accomplish complex tasks. However, due to the inherently unstable and unpredictable nature of LLM outputs, they may issue unintended tool commands or incorrect inputs, leading to potentially harmful operations. Unlike traditional security risks stemming from insecure user prompts, tool execution results from LLM-driven decisions introduce new and unique security challenges. These vulnerabilities span across all components of a computer-use agent. To mitigate these risks, we propose AgentSentinel, an end-to-end, real-time defense framework designed to mitigate potential security threats on a user's computer. AgentSentinel intercepts all sensitive operations within agent-related services and halts execution until a comprehensive security audit is completed. Our security auditing mechanism introduces a novel inspection process that correlates the current task context with system traces generated during task execution. To thoroughly evaluate AgentSentinel, we present BadComputerUse, a benchmark consisting of 60 diverse attack scenarios across six attack categories. The benchmark demonstrates a 87% average attack success rate on four state-of-the-art LLMs. Our evaluation shows that AgentSentinel achieves an average defense success rate of 79.6%, significantly outperforming all baseline defenses.
Adopting Large language models (LLMs) in organizations potentially revolutionizes our lives and work. However, they can generate off-topic, discriminating, or harmful content. This AI alignment problem often stems from misspecifications during the LLM adoption, unnoticed by the principal due to the LLM's black-box nature. While various research disciplines investigated AI alignment, they neither address the information asymmetries between organizational adopters and black-box LLM agents nor consider organizational AI adoption processes. Therefore, we propose LLM ATLAS (LLM Agency Theory-Led Alignment Strategy) a conceptual framework grounded in agency (contract) theory, to mitigate alignment problems during organizational LLM adoption. We conduct a conceptual literature analysis using the organizational LLM adoption phases and the agency theory as concepts. Our approach results in (1) providing an extended literature analysis process specific to AI alignment methods during organizational LLM adoption and (2) providing a first LLM alignment problem-solution space.
Generative Artificial Intelligence (GenAI) has rapidly transformed various fields including code generation, text summarization, image generation and so on. Agentic AI is a recent evolution that further advances this by coupling the decision making and generative capabilities of LLMs with actions that can be performed using tools. While seemingly powerful, Agentic systems often struggle when faced with numerous tools, complex multi-step tasks,and long-context management to track history and avoid hallucinations. Workflow patterns such as Chain-of-Thought (CoT) and ReAct help address this. Here, we define a novel agentic workflow pattern, AgentX, composed of stage designer, planner, and executor agents that is competitive or better than the state-of-the-art agentic patterns. We also leverage Model Context Protocol (MCP) tools, and propose two alternative approaches for deploying MCP servers as cloud Functions as a Service (FaaS). We empirically evaluate the success rate, latency and cost for AgentX and two contemporary agentic patterns, ReAct and Magentic One, using these the FaaS and local MCP server alternatives for three practical applications. This highlights the opportunities and challenges of designing and deploying agentic workflows.
The rapid advancement of large language models (LLMs) and domain-specific AI agents has greatly expanded the ecosystem of AI-powered services. User queries, however, are highly diverse and often span multiple domains and task types, resulting in a complex and heterogeneous landscape. This diversity presents a fundamental routing challenge: how to accurately direct each query to an appropriate execution unit while optimizing both performance and efficiency. To address this, we propose MoMA (Mixture of Models and Agents), a generalized routing framework that integrates both LLM and agent-based routing. Built upon a deep understanding of model and agent capabilities, MoMA effectively handles diverse queries through precise intent recognition and adaptive routing strategies, achieving an optimal balance between efficiency and cost. Specifically, we construct a detailed training dataset to profile the capabilities of various LLMs under different routing model structures, identifying the most suitable tasks for each LLM. During inference, queries are dynamically routed to the LLM with the best cost-performance efficiency. We also introduce an efficient agent selection strategy based on a context-aware state machine and dynamic masking. Experimental results demonstrate that the MoMA router offers superior cost-efficiency and scalability compared to existing approaches.
GPU kernel optimization has long been a central challenge at the intersection of high-performance computing and machine learning. Efficient kernels are crucial for accelerating large language model (LLM) training and serving, yet attaining high performance typically requires extensive manual tuning. Compiler-based systems reduce some of this burden, but still demand substantial manual design and engineering effort. Recently, researchers have explored using LLMs for GPU kernel generation, though prior work has largely focused on translating high-level PyTorch modules into CUDA code. In this work, we introduce Astra, the first LLM-based multi-agent system for GPU kernel optimization. Unlike previous approaches, Astra starts from existing CUDA implementations extracted from SGLang, a widely deployed framework for serving LLMs, rather than treating PyTorch modules as the specification. Within Astra, specialized LLM agents collaborate through iterative code generation, testing, profiling, and planning to produce kernels that are both correct and high-performance. On kernels from SGLang, Astra achieves an average speedup of 1.32x using zero-shot prompting with OpenAI o4-mini. A detailed case study further demonstrates that LLMs can autonomously apply loop transformations, optimize memory access patterns, exploit CUDA intrinsics, and leverage fast math operations to yield substantial performance gains. Our work highlights multi-agent LLM systems as a promising new paradigm for GPU kernel optimization.
Effective feedback, including critique and evaluation, helps designers develop design concepts and refine their ideas, supporting informed decision-making throughout the iterative design process. However, in studio-based design courses, students often struggle to provide feedback due to a lack of confidence and fear of being judged, which limits their ability to develop essential feedback-giving skills. Recent advances in large language models (LLMs) suggest that role-playing with AI agents can let learners engage in multi-turn feedback without the anxiety of external judgment or the time constraints of real-world settings. Yet prior studies have raised concerns that LLMs struggle to behave like real people in role-play scenarios, diminishing the educational benefits of these interactions. Therefore, designing AI-based agents that effectively support learners in practicing and developing intellectual reasoning skills requires more than merely assigning the target persona's personality and role to the agent. By addressing these issues, we present Feed-O-Meter, a novel system that employs carefully designed LLM-based agents to create an environment in which students can practice giving design feedback. The system enables users to role-play as mentors, providing feedback to an AI mentee and allowing them to reflect on how that feedback impacts the AI mentee's idea development process. A user study (N=24) indicated that Feed-O-Meter increased participants' engagement and motivation through role-switching and helped them adjust feedback to be more comprehensible for an AI mentee. Based on these findings, we discuss future directions for designing systems to foster feedback skills in design education.
Existing evaluation studies on linguistic competence of large language models (LLM agents) have focused primarily on vocabulary learning, morphological rule induction, syntactic generalization, pragmatic inference, and cross-linguistic transfer. However, none assess whether LLM agents can acquire a language through pattern recognition and interactive feedback, a central feature of human language acquisition. We propose a novel experimental framework in which an LLM agent is evaluated on its ability to acquire and use a newly constructed language (Tinkatongue) in conversation with a bot that understands only Tinkatongue. Our findings show that LLM agents fail to establish a conversation within 100 responses, yet they adopt distinct strategies that mirror human approaches to language learning. The results suggest a new direction for evaluation benchmarks and open pathways to model designs that learn more effectively from interactive feedback.
Foundation models, large language models (LLMs), and agentic AI systems rely heavily on vast corpora of user data. The use of such data for training has raised persistent concerns around ownership, copyright, and potential harms. In this work, we explore a related but less examined dimension: the ownership rights of data belonging to deceased individuals. We examine the current landscape of post-mortem data management and privacy rights as defined by the privacy policies of major technology companies and regulations such as the EU AI Act. Based on this analysis, we propose three post-mortem data management principles to guide the protection of deceased individuals data rights. Finally, we discuss directions for future work and offer recommendations for policymakers and privacy practitioners on deploying these principles alongside technological solutions to operationalize and audit them in practice.
Large language models (LLMs) have recently shown strong coding abilities, enabling not only static code generation but also iterative code self-evolving through agentic frameworks. Recently, AlphaEvolve \cite{novikov2025alphaevolve} demonstrated that LLM-based coding agents can autonomously improve algorithms and surpass human experts, with scopes limited to isolated kernels spanning hundreds of lines of code. Inspired by AlphaEvolve, we present SATLUTION, the first framework to extend LLM-based code evolution to the full repository scale, encompassing hundreds of files and tens of thousands of lines of C/C++ code. Targeting Boolean Satisfiability (SAT), the canonical NP-complete problem and a cornerstone of both theory and applications. SATLUTION orchestrates LLM agents to directly evolve solver repositories under strict correctness guarantees and distributed runtime feedback, while simultaneously self-evolving its own evolution policies and rules. Starting from SAT Competition 2024 codebases and benchmark, SATLUTION evolved solvers that decisively outperformed the human-designed winners of the SAT Competition 2025, and also surpassed both 2024 and 2025 champions on the 2024 benchmarks.
Large language models (LLMs) promise to accelerate UI design, yet current tools struggle with two fundamentals: externalizing designers' intent and controlling iterative change. We introduce SPEC, a structured, parameterized, hierarchical intermediate representation that exposes UI elements as controllable parameters. Building on SPEC, we present SpecifyUI, an interactive system that extracts SPEC from UI references via region segmentation and vision-language models, composes UIs across multiple sources, and supports targeted edits at global, regional, and component levels. A multi-agent generator renders SPEC into high-fidelity designs, closing the loop between intent expression and controllable generation. Quantitative experiments show SPEC-based generation more faithfully captures reference intent than prompt-based baselines. In a user study with 16 professional designers, SpecifyUI significantly outperformed Stitch on intent alignment, design quality, controllability, and overall experience in human-AI co-creation. Our results position SPEC as a specification-driven paradigm that shifts LLM-assisted design from one-shot prompting to iterative, collaborative workflows.
The National Comprehensive Cancer Network (NCCN) provides evidence-based guidelines for cancer treatment. Translating complex patient presentations into guideline-compliant treatment recommendations is time-intensive, requires specialized expertise, and is prone to error. Advances in large language model (LLM) capabilities promise to reduce the time required to generate treatment recommendations and improve accuracy. We present an LLM agent-based approach to automatically generate guideline-concordant treatment trajectories for patients with non-small cell lung cancer (NSCLC). Our contributions are threefold. First, we construct a novel longitudinal dataset of 121 cases of NSCLC patients that includes clinical encounters, diagnostic results, and medical histories, each expertly annotated with the corresponding NCCN guideline trajectories by board-certified oncologists. Second, we demonstrate that existing LLMs possess domain-specific knowledge that enables high-quality proxy benchmark generation for both model development and evaluation, achieving strong correlation (Spearman coefficient r=0.88, RMSE = 0.08) with expert-annotated benchmarks. Third, we develop a hybrid approach combining expensive human annotations with model consistency information to create both the agent framework that predicts the relevant guidelines for a patient, as well as a meta-classifier that verifies prediction accuracy with calibrated confidence scores for treatment recommendations (AUROC=0.800), a critical capability for communicating the accuracy of outputs, custom-tailoring tradeoffs in performance, and supporting regulatory compliance. This work establishes a framework for clinically viable LLM-based guideline adherence systems that balance accuracy, interpretability, and regulatory requirements while reducing annotation costs, providing a scalable pathway toward automated clinical decision support.
Large Language Models are increasingly used to simulate human opinion dynamics, yet the effect of genuine interaction is often obscured by systematic biases. We present a Bayesian framework to disentangle and quantify three such biases: (i) a topic bias toward prior opinions in the training data; (ii) an agreement bias favoring agreement irrespective of the question; and (iii) an anchoring bias toward the initiating agent's stance. Applying this framework to multi-step dialogues reveals that opinion trajectories tend to quickly converge to a shared attractor, with the influence of the interaction fading over time, and the impact of biases differing between LLMs. In addition, we fine-tune an LLM on different sets of strongly opinionated statements (incl. misinformation) and demonstrate that the opinion attractor shifts correspondingly. Exposing stark differences between LLMs and providing quantitative tools to compare them to human subjects in the future, our approach highlights both chances and pitfalls in using LLMs as proxies for human behavior.
We have reached a critical roadblock in the development and enhancement of long-horizon, multi-component LLM agentic systems: it is incredibly tricky to identify where these systems break down and why. Evaluation capabilities that currently exist today (e.g., single pass LLM-as-a-judge) are limited in that they often focus on individual metrics or capabilities, end-to-end outcomes, and are narrowly grounded on the preferences of humans. We argue that to match the agentic capabilities, evaluation frameworks must also be able to reason, probe, iterate, and understand the complex logic passing through these systems over long horizons. In this paper, we present RAFFLES - an evaluation architecture that incorporates reasoning and iterative refinement. Specifically, RAFFLES operates as an iterative, multi-component pipeline, using a central Judge to systematically investigate faults and a set of specialized Evaluators to assess not only the system's components but also the quality of the reasoning by the Judge itself, thereby building a history of hypotheses. We tested RAFFLES against several baselines on the Who&When dataset, a benchmark designed to diagnose the "who" (agent) and "when" (step) of a system's failure. RAFFLES outperforms these baselines, achieving an agent-step fault pair accuracy of over 43% on the Algorithmically-Generated dataset (a substantial increase from the previously published best of 16.6%) and over 20% on the Hand-Crafted dataset (surpassing the previously published best of 8.8%). These results demonstrate a key step towards introducing automated fault detection for autonomous systems over labor-intensive manual human review.
We develop a theory of intelligent agency grounded in probabilistic modeling for neural models. Agents are represented as outcome distributions with epistemic utility given by log score, and compositions are defined through weighted logarithmic pooling that strictly improves every member's welfare. We prove that strict unanimity is impossible under linear pooling or in binary outcome spaces, but possible with three or more outcomes. Our framework admits recursive structure via cloning invariance, continuity, and openness, while tilt-based analysis rules out trivial duplication. Finally, we formalize an agentic alignment phenomenon in LLMs using our theory: eliciting a benevolent persona ("Luigi'") induces an antagonistic counterpart ("Waluigi"), while a manifest-then-suppress Waluigi strategy yields strictly larger first-order misalignment reduction than pure Luigi reinforcement alone. These results clarify how developing a principled mathematical framework for how subagents can coalesce into coherent higher-level entities provides novel implications for alignment in agentic AI systems.
Molecular Tumor Boards (MTBs) are multidisciplinary forums where oncology specialists collaboratively assess complex patient cases to determine optimal treatment strategies. A central element of this process is the patient summary, typically compiled by a medical oncologist, radiation oncologist, or surgeon, or their trained medical assistant, who distills heterogeneous medical records into a concise narrative to facilitate discussion. This manual approach is often labor-intensive, subjective, and prone to omissions of critical information. To address these limitations, we introduce the Healthcare Agent Orchestrator (HAO), a Large Language Model (LLM)-driven AI agent that coordinates a multi-agent clinical workflow to generate accurate and comprehensive patient summaries for MTBs. Evaluating predicted patient summaries against ground truth presents additional challenges due to stylistic variation, ordering, synonym usage, and phrasing differences, which complicate the measurement of both succinctness and completeness. To overcome these evaluation hurdles, we propose TBFact, a ``model-as-a-judge'' framework designed to assess the comprehensiveness and succinctness of generated summaries. Using a benchmark dataset derived from de-identified tumor board discussions, we applied TBFact to evaluate our Patient History agent. Results show that the agent captured 94% of high-importance information (including partial entailments) and achieved a TBFact recall of 0.84 under strict entailment criteria. We further demonstrate that TBFact enables a data-free evaluation framework that institutions can deploy locally without sharing sensitive clinical data. Together, HAO and TBFact establish a robust foundation for delivering reliable and scalable support to MTBs.